50536-74-8

Upstream product

• 1004-66-6 2-methoxy-1,3-dimethylbenzene 
• 6994-63-4 2,6-dimethyl-3-nitro-phenol 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 67083-28-7 2,6-dimethyl-3-nitroaniline 

Downstream Products

• 295325-86-9 4-methoxy-5-methylindole 
• 639051-93-7 C₉H₁₃NO 
• 295325-87-0 4-methoxy-5-methylindoline 

Relevant academic research and scientific papers

HEPATITIS C INHIBITOR COMPOUNDS

Compounds of formula (I): wherein B, X, R3, L0, L1, L2, R2, R1 and RC are defined herein. The compounds are useful as inhibitors of HCV NS3 protease for the treatment of hepatitis C viral infection.

Effects of aromatic substituents on the photocleavage of 1-acyl-7-nitroindolines

Photolysis of 1-acyl-7-nitroindolines in aqueous solution gives a carboxylic acid and a 7-nitrosoindole. These compounds are useful as photolabile precursors of carboxylic acids, particularly neuroactive amino acids. The effect of electron-donating substituents at the 4-position has been explored for its effect on photolysis efficiency. 4-Methoxy substitution improved the photolysis efficiency >2-fold but the 4-dimethylamino analogue was essentially inert. A 5-alkyl substituent, that blocks unwanted nitration at this position, reduced the beneficial effect of the 4-methoxy group. (C) 2000 Elsevier Science Ltd.

Indole-carboxylic carbon compounds and pharmaceutical compositions containing them

Indole-carboxylic acid compounds of the formula: STR1 wherein R1 is lower alkyl or alkoxy radical or halogen; R2 is halogen; lower alkyl or alkoxy radical; or R1 and R2 can together also form an alkylene bridge containing 3 to 5 carbon atoms, which can optionally contain one or more double bonds; and, but less preferably, when R1 is a lower alkyl or alkoxy radical, R2 can also be a hydrogen atom, and physiologically compatible salts and esters thereof, Are outstandingly effective as blood sugar-lowering agents.