506-52-5

Usage

Uses

1. Used in Pharmaceutical Applications:
1-Hexacosanol is used as a therapeutic agent for reducing Parkinson's symptoms, as it has shown potential in contributing to the modulation of the release of proinflammatory mediators.
2. Used in Anti-Inflammatory Applications:
1-Hexacosanol is used as an anti-inflammatory agent, as it contributes to the modulation of the release of proinflammatory mediators, potentially providing relief from inflammation-related conditions.
3. Used in Cosmetics Industry:
1-Hexacosanol is used as an ingredient in the cosmetics industry, due to its long-chain primary fatty alcohol structure, which can provide moisturizing and emollient properties to various cosmetic products.
4. Used in Chemical Research:
1-Hexacosanol is used as a research compound in the field of organic chemistry, particularly for studying the properties and reactions of long-chain primary alcohols and their derivatives.

InChI:InChI=1/C29H58O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-29(32)33-27-28(31)26-30/h28,30-31H,2-27H2,1H3/t28-/m0/s1

Upstream product

• 5802-82-4 methyl hexacosanoate 
• 822-32-2 n-hexacosanol acetate 
• 102945-07-3 2-octadecylthiophene 
• 112-95-8 icosane 
• 629-97-0 n-docosane 
• 630-01-3 n-hexacosane 
• 593-45-3 octadecane 
• 646-31-1 tetracosane 
• 630-02-4 octacosane 
• 638-68-6 n-triacontane 
• 629-50-5 Tridecane 
• 111514-94-4 3-[2-(5-Octadecyl-thiophen-2-yl)-[1,3]dithiolan-2-yl]-propionic acid methyl ester 
• 111514-83-1 4-(5-Octadecyl-thiophen-2-yl)-4-oxo-butyric acid methyl ester 
• 116577-41-4 sodium salt of 12-bromododecanoic acid 

Downstream Products

• 822-32-2 n-hexacosanol acetate 
• 74602-26-9 hexacosyl p-methoxy cinnamate 
• 74602-25-8 hexacosyl p-acetoxy cinnamate 
• 7719-79-1 dopentacontane 
• 26627-85-0 hexacosanal 
• 58886-94-5 n-hexacosanyl n-octadecanoate 
• 506-46-7 1-hexacosanoic acid 
• 4276-51-1 1-Brom-hexacosan 

Relevant academic research and scientific papers

METHOD FOR THE PRODUCTION OF PRIMARY LONG-CHAIN ALCOHOLS

The invention relates to a method for the production of linear long-chain alcohols with 20 to 40 carbon atoms by means of a growth reaction with ethylene on aluminium compounds.

PROCESS FOR THE PREPARATION OF ALIPHATIC PRIMARY ALCOHOLS AND RELATED INTERMEDIATES IN SUCH PROCESS

The invention relates to protected alcohol with formula (R1 - O-)mPG, wherein R1 represents a linear, straight-chain alkyl group having 26-30 C-atoms, m is 1 or 2, and PG, forming an ether group in combination with the -O- of the former primary alcohol, represents a protecting group chosen from the group of substituted methyl, substituted ethyl, substituted benzyl and (substituted) silyl groups with at least one substituent on the Si-atom being not a methyl group, in case m = 1; and a diol protecting group in case m = 2, with the proviso that PG is no saccharide. The invention further relates to process for the preparation of such protected alcohols via an organometallic cross coupling reaction.

Synthesis of even C24-C30 primary normal aliphatic alcohols from cyclododecanone

A simple method has been developed for the oxidation of cyclododecanone by sodium persulfate in an aqueous methanol solution of sulfuric acid to give 12-hydroxydodecanoic acid, which upon treatment with HBr in acetic acid gives 12-bromododecanoic acid with RMgX, where R=C12H25, C14H29, C16H33, and C18H37 in THF in the presence of Li2CuCl4 and subsequent reduction of the salts of the alkanecarboxylic acids by LiAlH4 give primary even normal C24-C30 alcohols.

A New Synthesis of Long Chain Acid Esters and Carbinols

A versatile synthesis of difficulty accessible long chain acid esters and carbinols is described.The synthesis involves acylations at 2- and 5-positions of thiophene.Thioketalation of the resulting ketoesters followed by Raney nickel desulfurization yield acid esters which on LAH reduction give the corresponding carbinols.