50609-54-6

Basic information

• Product Name: 1-Oxo-1H-pyrimido[1,2-a]quinoline-2-acetic acid ethyl ester
• Synonyms: 1-Oxo-1H-pyrimido[1,2-a]quinoline-2-acetic acid ethyl ester
• CAS NO: 50609-54-6
• Molecular Formula: C16H14N2O3
• Molecular Weight: 282.29
• Mol File: 50609-54-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Oxo-1H-pyrimido[1,2-a]quinoline-2-acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Oxo-1H-pyrimido[1,2-a]quinoline-2-acetic acid ethyl ester(50609-54-6)
• EPA Substance Registry System: 1-Oxo-1H-pyrimido[1,2-a]quinoline-2-acetic acid ethyl ester(50609-54-6)

Safety Data

• Hazardous Substances Data: 50609-54-6(Hazardous Substances Data)

Upstream product

• 50609-53-5 (quinolin-2-ylamino-methylene)-succinic acid diethyl ester 

Relevant articles and documents

Nitrogen Bridgehead Compounds. Part 6. Ring Transformation. Part 3. Thermal Cyclization of Diethyl 2-(2-Pyridylaminomethylene)-succinates and -glutarates

The pyridylsuccinates (1) and pyridylglutarates (2), with various substituents on the pyridine ring, were cyclized in Dowtherm A at 250 deg C.The succinates cyclized in two competing reaction routes, giving rise to pyridopyrimidines (route A) and N-pyridylpyrrolinones (route B).The ratio of the two products varied with the nature of the substituent and its position.The N-pyridylpyrrolinones proved to be mixtures of the desmotropes (5) and (6) which were separated.The pyridylglutarates (2) gave only the pyridopyrimidines (4).The 6-substituted pyridopyrimidines underwent a ring-transformation reaction at or above 250 deg C, forming the corresponding 1,8-naphthyridines (8) and (9).