50609-59-1Relevant articles and documents
Nitrogen Bridgehead Compounds. Part 74. Cyclization of 2-(2-Pyridylaminomethylene)succinates in Ethanolic Sodium Ethoxide. Part 2. Michael Addition of Pyridyldihydropyrrolones
Vasvari-Debreczy, Lelle,Hermecz, Istvan,Podanyi, Benjamin,Eroes-Takacsy, Tuende
, p. 2019 - 2022 (2007/10/02)
2-(2-Pyridylaminomethylene)succinates, which in ethanolic sodium ethoxide solution yielded equilibrium mixtures of the pyridopyrimidines (3) and the pyridyldihydropyrrolones (5) and (6), within 15 min, furnished a dihydropyrrolone dimer as the main product on longer (>=2 h) reaction.The dimer had the unusual 4,4'-connection between the five-membered rings, and was shown to be the pure trans-diastereoisomer (7); it is considered to be formed by a Michael addition reaction of the pyrrolones (5) and (6).These longer reactions are accompained by hydrolytic processes.
STERIC EFFECTS IN THE RING CLOSURE REACTIONS OF 2-(2-PYRIDYLAMINOMETHYLENE)SUCCINATES
Vasvari-Debreczy, Lelle,Hermecz, Istvan,Meszaros, Zoltan
, p. 740 (2007/10/02)
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