50629-10-2Relevant academic research and scientific papers
ACYLATION AND BROMINATION OF SOME 2-MERCAPTOTHIENOPYRIMIDINONES AND SYNTHESIS OF THEIR 2-AMINO DERIVATIVES
Khripak, S. M.,Yakubets, V. I.,Dobosh, A. A.
, p. 1091 - 1094 (2007/10/02)
The acylation of 2-thio-3-R-4-oxo-3,4-dihydrothieno-pyrimidines by means of benzoyl chloride was studied.Depending on the reaction conditions, it may take place with formation of S-substituted and N-substituted derivatives.The bromination of the sodium salts of thienopyrimidines and their S- and N-substituted derivatives is accompanied by the formation of disulfides, which do not react with electrophilic reagents but react with amines to give 2-amino derivatives of thienopyrimidines.
