50630-61-0

Upstream product

• 50630-62-1 5,5-dimethyl-2,3,4,5-tetrahydro-2,4-furandione 
• 62-53-3 aniline 
• 72601-11-7 4-hydroxy-4-methyl-pent-2-ynoic acid ethyl ester 

Downstream Products

• 50630-62-1 5,5-dimethyl-2,3,4,5-tetrahydro-2,4-furandione 
• 62-53-3 aniline 

Relevant academic research and scientific papers

Facile reaction of thiols and amines with alkyl 4-hydroxy-2-alkynoates in water under neutral conditions and ultrasound irradiation

This Letter describes an alternative protocol for the Michael addition of thiols to 4-hydroxy-2-alkynoates. The reaction proceeds at room temperature in water under ultrasound irradiation. With amines instead of thiols a sequential conjugate addition/lact

Reaction of enaminones with benzyltrimethylammonium dichloroiodate

Reaction of enaminones with benzyltrimethylammonium dichloroiodate (BTMA·ICl2) in methylene chloride-methanol in the presence of sodium bicarbonate at room temperature gave iodinated products at the α-position of the carbonyl group in good yiel

Enaminones as potential prodrugs of primary and secondary amines

Novel enzymatically labile enaminones useful as potential prodrugs of primary and secondary amines are disclosed. Also, disclosed herein are compositions comprising said amines and methods of administering said composition to warm-blooded animals.