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Luteolin 7-apiosyl-(1->2)-glucoside is a flavonoid glycoside, a type of polyphenolic compound, found in various plant sources such as fruits, vegetables, and herbs. It possesses antioxidant and anti-inflammatory properties and has been studied for its potential health benefits, including protection against oxidative stress and inflammation, as well as its role in preventing chronic diseases like cancer and cardiovascular disease. Additionally, luteolin 7-apiosyl-(1->2)-glucoside has been investigated for its neuroprotective effects and its ability to modulate immune function, making it a promising natural compound with a range of health-promoting effects.

506410-53-3

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506410-53-3 Usage

Uses

Used in Pharmaceutical Industry:
Luteolin 7-apiosyl-(1->2)-glucoside is used as a therapeutic agent for its potential role in preventing chronic diseases such as cancer and cardiovascular disease. Its antioxidant and anti-inflammatory properties contribute to its health-promoting effects.
Used in Nutraceutical Industry:
Luteolin 7-apiosyl-(1->2)-glucoside is used as a dietary supplement or functional food ingredient due to its potential health benefits, including protection against oxidative stress and inflammation.
Used in Cosmetic Industry:
Luteolin 7-apiosyl-(1->2)-glucoside is used as an active ingredient in skincare products for its antioxidant and anti-inflammatory properties, which may help protect the skin from environmental stressors and promote skin health.
Used in Neuroprotective Applications:
Luteolin 7-apiosyl-(1->2)-glucoside is used as a neuroprotective agent for its potential to protect the nervous system and support cognitive function.
Used in Immunomodulatory Applications:
Luteolin 7-apiosyl-(1->2)-glucoside is used as an immunomodulatory agent for its ability to modulate immune function, potentially contributing to the regulation of immune responses and overall immune health.

Check Digit Verification of cas no

The CAS Registry Mumber 506410-53-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,6,4,1 and 0 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 506410-53:
(8*5)+(7*0)+(6*6)+(5*4)+(4*1)+(3*0)+(2*5)+(1*3)=113
113 % 10 = 3
So 506410-53-3 is a valid CAS Registry Number.

506410-53-3Upstream product

506410-53-3Downstream Products

506410-53-3Relevant academic research and scientific papers

Absorption and Metabolism of Luteolin in Rats and Humans in Relation to in Vitro Anti-inflammatory Effects

Hayasaka, Natsumi,Shimizu, Naoki,Komoda, Toshikazu,Mohri, Satoshi,Tsushida, Tojiro,Eitsuka, Takahiro,Miyazawa, Teruo,Nakagawa, Kiyotaka

, p. 11320 - 11329 (2018)

Luteolin is a flavonoid present in plants in the form of aglycone or glucosides. In this study, luteolin glucosides (i.e., luteolin-7-O-β-d-glucoside, luteolin-7-O-[2-(β-d-apiosyl)-β-d-glucoside], and luteolin-7-O-[2-(β-d-apiosyl)-6-malonyl-β-d-glucoside]) prepared from green pepper leaves as well as luteolin aglycone were orally administered to rats. Regardless of the administered luteolin form, luteolin glucuronides were mainly detected from plasma and organs. Subsequently, luteolin aglycone, the most absorbed form of luteolin in rats, was orally administered to humans. As a result, luteolin-3′-O-sulfate was mainly identified from plasma, suggesting that not only luteolin form but also animal species affect the absorption and metabolism of luteolin. When LPS-treated RAW264.7 cells were treated with luteolin glucuronides and luteolin sulfate (the characteristic metabolites identified from rats and humans, respectively), the different luteolin conjugates were metabolized in different ways, suggesting that such difference in metabolism results in their difference in anti-inflammatory effects.

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