506441-97-0Relevant academic research and scientific papers
Synthesis of lipid A derivatives and their interactions with polymyxin B and polymyxin B nonapeptide
Yin, Ning,Marshall, Ryan L.,Matheson, Sannali,Savage, Paul B.
, p. 2426 - 2435 (2007/10/03)
Lipid A is the causative agent of Gram-negative sepsis, a leading cause of mortality among hospitalized patients. Compounds that bind lipid A can limit its detrimental effects. Polymyxin B, a cationic peptide antibiotic, is one of the simplest molecules c
