506449-82-7Relevant articles and documents
Synthesis of the acyl side chain segment of polyoxypeptins using regioselective ring-opening of chiral 2,3-epoxy alcohol
Makino, Kazuishi,Suzuki, Tatsuya,Awane, Shinobu,Hara, Osamu,Hamada, Yasumasa
, p. 9391 - 9395 (2002)
The acyl side chain segment 2 contained in polyoxypeptins A (1a) and B (1b), apoptosis-inducing cyclodepsipeptides, was synthesized from chiral 2,3-epoxy alcohol (6), easily prepared by Sharpless asymmetric epoxidation, through a regioselective ring-opening reaction as the key step.