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1-Chloro-3-isopropylamino-2-propanol, commonly known as chloroprocaine, is a local anesthetic and a potent sodium channel blocker. It is characterized by its rapid onset and short duration of action, making it a preferred choice for various medical procedures that require quick anesthesia and fast recovery time.

50666-68-7

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50666-68-7 Usage

Uses

Used in Anesthesiology:
1-Chloro-3-isopropylamino-2-propanol is used as a local anesthetic for spinal and epidural anesthesia during childbirth and various surgical procedures. It works by preventing the transmission of pain signals from nerve endings to the brain, resulting in temporary numbness in the affected areas.
Used in Childbirth:
Chloroprocaine is used as a local anesthetic for spinal and epidural anesthesia during childbirth. Its rapid onset and short duration of action make it suitable for labor and delivery, providing effective pain relief while allowing for a quick recovery.
Used in Surgical Procedures:
1-Chloro-3-isopropylamino-2-propanol is used as a local anesthetic for various surgical procedures. Its ability to block sodium channels and prevent pain signal transmission makes it an effective choice for surgeries that require quick anesthesia and minimal side effects.
However, it is important to note that chloroprocaine can cause side effects such as hypotension, headache, and dizziness. Therefore, it should be used with caution in individuals with certain medical conditions. Despite these potential side effects, chloroprocaine remains an important and widely used chemical in the field of anesthesiology.

Check Digit Verification of cas no

The CAS Registry Mumber 50666-68-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,6,6 and 6 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 50666-68:
(7*5)+(6*0)+(5*6)+(4*6)+(3*6)+(2*6)+(1*8)=127
127 % 10 = 7
So 50666-68-7 is a valid CAS Registry Number.

50666-68-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-chloro-3-(propan-2-ylamino)propan-2-ol

1.2 Other means of identification

Product number -
Other names 3-isopropylamino-2-hydroxy-1-chloropropane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:50666-68-7 SDS

50666-68-7Relevant academic research and scientific papers

Switchable synthesis of cyclic carbamates by carbon dioxide fixation at atmospheric pressure

Toda, Yasunori,Shishido, Minoru,Aoki, Tatsuya,Sukegawa, Kimiya,Suga, Hiroyuki

supporting information, p. 6672 - 6675 (2021/07/13)

The base-promoted switchable synthesis of five- and six-membered cyclic carbamates using atmospheric pressure carbon dioxide as the C1 source was developed. The chemoselectivity of products was simply controlled by changing bases and solvents. The reaction proceeds effectively under mild conditions, affording valuable cyclic carbamates. Experimental results and DFT studies revealed the reaction mechanism.

The illumination optical system, the exposure device and method of manufacturing the device

-

, (2007/10/05)

PROBLEM TO BE SOLVED: To provide: an illumination optical system adjusting the pupil intensity distribution on an irradiated surface; an aligner; and a method of manufacturing device. SOLUTION: The illumination optical system 13 includes: an optical integrator 28 for forming a secondary light source 30 on an illuminated pupil surface 29 in an illumination optical path of the illumination optical system 13 in the case where an exposing light EL from a light source device 12 is incident; a light-shielding unit constituted of a plurality of mutually displaceable light-shielding members which are disposed in an optical path of the exposing light EL emitted from the secondary light source 30 such that quantities of shielded light are different from one another depending on the incidence angle of the exposing light EL; and a replacement mechanism 59 individually displacing the light-shielding members in the light-shielding unit in the optical path of the exposing light EL. COPYRIGHT: (C)2010,JPOandINPIT

Preparation of 3-Azetidinols with Non-Bulky 1-Alkyl Substituents

Higgins, Robert H.,Eaton, Quentin L.,Worth, Leroy,Peterson, Myra V.

, p. 255 - 259 (2007/10/02)

Cyclization of either the tetrahydropyranyl or trimethylsilyl ether of 1-(alkylamino)-3-chloro-2-propanols 1 followed by cleavage of the azetidinyl ether provides a general method for the preparation of 1-alkyl-3-azetidinols.Unhindered amines provide a more facile preparation of derivatives of 1, or its ethers, than do hindered amines, while hindered derivatives of 1 undergo more facile ring closure.

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