50677-95-7

Upstream product

• 77735-17-2 2-acetamido-1,6-anhydro-3-O-benzyl-2-deoxy-4-O-(tetrahydro-2-pyranyl)-β-D-glucopyranose 
• 77735-15-0 2-acetamido-3-O-acetyl-1,6-anhydro-2-deoxy-4-O-(tetrahydro-2-pyranyl)-β-D-glucopyranose 
• 77735-16-1 2-acetamido-1,6-anhydro-2-deoxy-4-O-(tetrahydro-2-pyranyl)-β-D-glucopyranose 
• 55682-47-8 1,6-anhydro-2-azido-4-O-benzyl-2-deoxy-β-D-glucopyranose 
• 50604-68-7 2-acetamido-3-O-acetyl-1,6-anhydro-4-O-benzyl-2-deoxy-β-D-glucopyranose 
• 37042-50-5 2-acetamido-3-O-acetyl-1,6-anhydro-2-deoxy-β-D-glucopyranose 
• 33208-47-8 4-O-benzyl-1,6:2,3-dianhydro-β-D-mannopyranose 
• 50604-73-4 2-Acetamido-1,6-anhydro-3-O-benzyl-2-desoxy-β-D-glucopyranose 
• 3068-32-4 1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside 
• 108-24-7 acetic anhydride 

Relevant academic research and scientific papers

Synthesis of 2-Acetamido-2-deoxy-4-O-β-D-galactopyranosyl-D-glucopyranose (N-Acethyllactosamine) Derivatives

In order to provide useful key intermediates for synthesises of complex oligosaccharides, anomeric 1,2',3',4',6,6'-hexa-O-acetyl-N-acetyllactosamines (8:α, and 9:β) and the corresponding 3-O-benzyl ethers (5:α, and 6:β) were synthesized.Condensation of 1,6-anhydro-3-O-benzyl-β-N-acetylglucosamine with acetobromogalactose by a conventional Koenigs-Knorr procedure, followed by selective acetolysis of the 1,6-anhydro-β-linkage, provided 5 and 6.Debenzylation of 5 and 6 gave 8 and 9, respectively.Keywords - Koenigs-Knorr synthesis; 1,6-anhydro-3-O-benzyl-β-N-acetylglucosamine; 1,6-anhydro-β-N-acetyllactosamine derivative; anomeric octaacetyllactosamine; anomeric heptaacetyllactosamine; anomeric 3-O-benzyl-heptaaetyllactosamine