50684-45-2

Upstream product

• 1711-06-4 3-Methylbenzoyl chloride 

Downstream Products

• 1259992-59-0 C₆H₄CH₃COSNHCOC₆H₅ 
• 1211-32-1 2-(m-tolyl)benzo[d]thiazole 
• 79293-03-1 phenylmercury 3-methylthiobenzoate 
• 37864-41-8 potassium 3-methylbenzothioate 
• 103199-97-9 C₁₄H₁₂OSSe 

Relevant academic research and scientific papers

Rhodium-catalyzed regioselective addition of thioacids to terminal allenes: Enantioselective access to branched allylic thioesters

Rhodium-catalyzed regio-and enantioselective hydrothiolation of terminal allenes with thioacids is reported for the atom-economic synthesis of chiral branched allylic thioesters. By using a rhodium(i) catalyst system, diversities of terminal allenes and thioacids afforded the corresponding branched thioesters in excellent regioselectivity, high yield, and good enantioselectivity. This method was also explored for Fmoc-protected aminothioacids for diastereoselective synthesis of the corresponding thioesters.

2-arylalkylthio -imidazoles, 2-arylalkenyl -thio -imidazoles and 2-arylalkinyl -thio -imidazoles as anti -inflammatory substances and substances inhibiting the release of cytokine

The invention relates to 4-heteroaryl-5-phenylimidazole derivatives having 2-arylalkylthio, 2-arylalkenylthio and 2-arylalkynylthio substitution, of the general formula I: in which Ar is a phenyl radical, Het is a hetero aromatic radical, A is an alkylene chain, R1 is an alkylthio, alkylsulfinyl, alkylsulfonyl, sulfonamido or alkylcarbonyl group and R2 is an alkyl, hydroxyl, alkoxy, alkoxycarbonyl, sulfonamido, carboxyl, nitro or aminocarbonyl group or a halogen atom. n can be 1 or 2 and m is 0 to 2. The compounds according to the invention show antiinflammatory activity.