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50690-52-3

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50690-52-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 50690-52-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,6,9 and 0 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 50690-52:
(7*5)+(6*0)+(5*6)+(4*9)+(3*0)+(2*5)+(1*2)=113
113 % 10 = 3
So 50690-52-3 is a valid CAS Registry Number.

50690-52-3Relevant academic research and scientific papers

Synthesis and thermal properties of twin dimers containing cyanostilbene derivatives as a mesogenic group

Mihara,Ito,Koide

, p. 69 - 85 (2007/10/03)

We synthesized twin dimers (TDs) with different linking groups between a mesogenic group and a flexible spacer, different spacer length, and different terminal alkyl chain length to clarify the effect of these groups on the mesomorphic properties of the T

Design, synthesis and antiproliferative activity of tripentones: A new series of antitubulin agents

Lisowski, Vincent,Enguehard, Cecile,Lancelot, Jean-Charles,Caignard, Daniel-Henri,Lambel, Stephanie,Leonce, Stephane,Pierre, Alain,Atassi, Ghanem,Renard, Pierre,Rault, Sylvain

, p. 2205 - 2208 (2007/10/03)

Structure-activity relationship studies of a new series of tripentones (thieno[2,3-b]pyrrolizin-8-ones), led us to prepare several derivatives with antiproliferative activities. The most promising 3-(3-hydroxy-4-methoxyphenyl)thieno[2,3-b]pyrrolizin-8-one 20 (leukemia L1210, IC50 = 15 nM) was shown to be a potent inhibitor of tubulin polymerization.

Design of Inhibitors from the Three-Dimensional Structure of Alcohol Dehydrogenase. Chemical Synthesis and Enzymatic Properties

Freudenreich, Charles,Samama, Jean-Pierre,Biellmann, Jean-Francois

, p. 3344 - 3353 (2007/10/02)

Inhibitors of liver alcohol dehydrogenase were designed from the three-dimensional structure of the enzyme.The ligand to the catalytic zinc ion is an amide group or, better, a formamide group.With the latter function, a hydrogen bond between the NH group and the hydroxyl group of Ser-48 may be formed.The hydrophobic substrate binding site brings structural restraints. α-ω bifunctional molecules show good inhibitory properties possibly due to the interactions with polar residues at the entrance of the substrate binding site.

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