50692-68-7Relevant academic research and scientific papers
Enzymatic synthesis of Ga1β1→3GlcNAc derivatives utilising a phosphorylase from Bifidobacterium bifidum 20082
Farkas, Erzsébct,Thiem, Joachim,Krzewinski, Frédéric,Bouquelet, Stéphane
, p. 728 - 730 (2007/10/03)
The stereo- and regiospecific synthesis of Galβ1→3GlcNAc derivatives was achieved in up to 57% yield employing the β-1→3-galactosyl-N- acetylhexosamine phosphorylase from Bifidobacterium bifidum DSM 20082.
Galactosylation with β-Galactosidase from bovine testes employing modified acceptor substrates
Gambert, Ulrike,Gonzalez Lio, Raul,Farkas, Erzsebet,Thiem, Joachim,Verez Bencomo, Vicente,Liptak, Andras
, p. 1285 - 1291 (2007/10/03)
In this study β1-3 linked analogues of the T-antigen determinant were synthesized in preparative scale by transgalactosylation using β-galactosidase from bovine testes to give synthetic antigens. Accepters with modifications of the sugar residue such as α-glycosylated spacers, as well as GlcNAc-αOR- and 2dGal-αOR-substrates opened further possibilities for galactosylation.
