5070-30-4Relevant academic research and scientific papers
Diverse Oxidative C(sp2)-N Bond Cleavages of Aromatic Fused Imidazoles for Synthesis of α-Ketoamides and N-(pyridin-2-yl)arylamides
Xu, Fangzhou,Wang, Yanyan,Xun, Xiwei,Huang, Yun,Jin, Zhichao,Song, Baoan,Wu, Jian
, p. 8411 - 8422 (2019/05/17)
An efficient and chemoselective C(sp2)-N bond cleavage of aromatic imidazo[1,2-a]pyridine molecules is developed. A broad scope of amide compounds such as α-ketoamides and N-(pyridin-2-yl)arylamides are afforded as the final products in up to quantitative yields. Diverse C-N bond cleavages are controlled by the oxidative species used in this transformation, with various amide products afforded in a chemoselective fashion. A preliminary study indicated that some α-ketoamides exhibit anti-Tobacco Mosaic Virus activity for potential use in plant protection.
Preparation method of alpha-carbonyl amide derivatives
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Paragraph 0087-0089; 0130-0132, (2019/01/14)
The invention discloses a preparation method of alpha-carbonyl amide derivatives. According to the method, pyridino-aminoimidazole compounds and water are subjected to ring-opening reaction under theaction of an oxidizing agent, meanwhile, oxygen atoms ar
THE SYNTHESES OF N-FREE α-DEHYDROAMINO ACID ESTERS AND N-ACETYL DEHYDRODIPEPTIDE ESTER FROM N-CARBOXY α-DEHYDROAMINO ACID ANHYDRIDE
Shin, Chung-gi,Yonezawa, Yasuchika,Yoshimura, Juji
, p. 1635 - 1638 (2007/10/02)
N-Carboxy α-dehydroamino acid anhydride, derived from N-benzyloxycarbonyl α-dehydroamino acid (DHA) and thionyl chloride, was found to be very useful for the synthesis of N-free DHA ester by alcoholysis and N-acetyl dehydrodipeptide ester by coupling was
