507446-95-9Relevant articles and documents
Synthesis of benzoxazolones from nitroarenes or aryl halides
Porzelle, Achim,Woodrow, Michael D.,Tomkinson, Nicholas C. O.
supporting information; experimental part, p. 812 - 815 (2010/04/24)
Chemical equation presented A simple and effective method for the preparation of benzoxazolones from nitroarenes or aryl halides is described. Partial reduction of a nitro group in the presence of a chloroformate followed by a microwave-assisted rearrangement/ring closure sequence provides a convenient and practical procedure to prepare this important pharmacophore. Rearrangement precursors were also accessed from aryl halides through transitionmetal-catalyzed coupling.