50790-97-1

Upstream product

• 74904-16-8 2-Methyl-4a-phenyl-2,3,4,4a,5,6,7,8-octahydro-isoquinoline 
• 28289-54-5 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine 
• 84978-87-0 2-methyl-4a-phenyl-3-oxo-transdecahydroisoquinoline 
• 74904-26-0 Acetate(4aS,8aR)-2-methyl-4a-phenyl-3,4,4a,5,6,7,8,8a-octahydro-isoquinolinium; 
• 117661-09-3 4a-phenyl-3-oxo-transdecahydroisoquinoline 
• 74904-10-2 4-(4-Chloro-butyl)-1-methyl-4-phenyl-1,2,3,4-tetrahydro-pyridine 
• 854718-87-9 6-(2-ethoxy-ethyl)-6-phenyl-cyclohex-1-enecarbonitrile 
• 591-51-5 phenyllithium 
• 17488-64-1 3-phenyl-cyclohex-2-enol 
• 10345-87-6 3-phenylcyclohex-2-enone 
• 5323-87-5 3-Ethoxycyclohex-2-en-1-one 
• 95514-62-8 (E)-ethyl hepta-2,6-dienoate 
• 97523-18-7 (4aS,6S,8aS)-6-Methylsulfanylthiocarboxyoxy-4a-phenyl-octahydro-isoquinoline-2-carboxylic acid ethyl ester 
• 97523-16-5 (4aS,6S,8aS)-6-Formyloxy-4a-phenyl-octahydro-isoquinoline-2-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

An Efficient Diastereoselective Synthesis of 6-Hydroxy-4a-phenyl-cis-decahydroisoquinolines through N-Acyliminium Ion Induced Polyene Cyclization

The two kinds of carbamates 13a,b and 18a,b were prepared from acidc 11 and 17, respectively, through the Curtius method via the corresponding acid azides.Cyclization of 13a,b and 18a,b with paraformaldehyde-formic acid afforded 4a-phenyl-cis-decahydroiso

A NEW AND FACILE STEREOSELECTIVE SYNTHESIS OF CIS-4a-ARYL-1,2,3,4,4a,5,6,8a-OCTAHYDROISOQUINOLINE DERIVATIVES

Cis-1,2,3,4,4a,5,6,8a-octahydro-2-methyl-4a-phenylisoquinolin-3-one was obtained by cyclization of the acyliminium ion intermediate, derived from the corresponding amide.Reduction of this cyclization product with LiAlH4 in THF afforded cis-1,2,3,4,4a,5,6,8a-octahydro-2-methyl-4a-phenylisoquinoline.In a similar way, the octahydro-4a-(2-methoxyphenyl)-isoquinolin-3-one was also prepared from the corresponding amide.