508204-89-5

Upstream product

• 508204-84-0 (1S,2S,6R,7S,9S)-4,4-Dimethyl-8-((R)-1-phenyl-ethyl)-3,5-dioxa-8-aza-tricyclo[5.2.2.0^2,6]undecane-9-carboxylic acid ethyl ester 
• 851389-16-7 ethyl (1S,3S,4S,5S,6R)-5,6-dihydroxy-2-[(1R)-1-phenylethyl]-2-azabicyclo[2.2.2]octane-3-carboxylate 
• 134984-64-8 exo-2-aza-2-<(R)-1-phenylethyl>-3-ethoxycarbonyl<2.2.2>bicyclooct-5-ene 
• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 508204-87-3 (1S,2S,6R,7S,9S)-4,4-Dimethyl-3,5-dioxa-8-aza-tricyclo[5.2.2.0^2,6]undecane-9-carboxylic acid ethyl ester 

Downstream Products

• 508205-10-5 (6S,7S,9aS)-7-Formyl-1-hydroxy-4-oxo-octahydro-pyrido[1,2-a]pyrazine-2,6-dicarboxylic acid 2-benzyl ester 6-ethyl ester 
• 508204-96-4 ethyl (1S,3S,4S,5S,6R)-2-(2-benzyloxycarbonylaminoacetyl)-5,6-dihydroxy-2-azabicyclo[2.2.2]octane-3-carboxylate 

Relevant academic research and scientific papers

Short and efficient synthesis of diazabicycloalkane dipeptide mimics

A new synthetic route to enantiomerically pure diazabicycloalkanes is reported. Key step of this synthesis is an oxidative cleavage of azabicycloalkene precursors that are synthesized in enantiomerically pure form via aza-Diels-Alder reaction. A range of diazabicycloalkanes with different amino acid side chains have been synthesized and their structure has been elucidated by NMR analysis.