50825-78-0Relevant academic research and scientific papers
Method for preparing monofatty acid glyceride citrate in aqueous phase
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Paragraph 0028; 0031-0033; 0036-0038; 0041-0043; 0046-0048, (2019/07/04)
The invention provides a method for preparing monofatty acid glyceride citrate in an aqueous phase. The method comprises the steps: adding epichlorohydrin and citric acid as starting raw materials, and performing two steps of reactions including esterification and ring opening in the presence of a reaction aid in an aqueous phase so as to produce the monofatty acid glyceride citrate. According tothe method for preparing the monofatty acid glyceride citrate in an aqueous phase, the cheap and easily available epichlorohydrin is adopted as a starting raw material, a reaction is performed on theepichlorohydrin with citric acid in the presence of polytetrafluoroethylene particles (PTFE), a phase transfer catalyst and alkali in the aqueous environment so as to obtain a compound 1 quantitatively, and then the ring-opening reaction is performed on the compound 1 and stearic acid so as to prepare the monofatty acid glyceride citrate; and the preparation method has mild reaction conditions, easily available reaction reagents, a high reaction yield and high selectivity, and the final product has high purity and a broad commercial application prospect.
