50849-45-1

Basic information

• Product Name: meso-Tetra(3-methylphenyl) porphine
• Synonyms: meso-Tetra(3-methylphenyl) porphine;21H,23H-Porphine, 5,10,15,20-tetrakis(3-methylphenyl)-;5,10,15,20-tetrakis(3-methylphenyl)porphyrin;5,10,15,20-tetrakis(meta-tolyl)porphyrin
• CAS NO: 50849-45-1
• Molecular Formula: C₄₈H₃₈N₄
• Molecular Weight: 670.84212
• Mol File: 50849-45-1.mol

Chemical Properties

• Melting Point: >300 °C
• Appearance: /
• Density: 1 +-.0.06 g/cm3(Predicted)
• CAS DataBase Reference: meso-Tetra(3-methylphenyl) porphine(CAS DataBase Reference)
• NIST Chemistry Reference: meso-Tetra(3-methylphenyl) porphine(50849-45-1)
• EPA Substance Registry System: meso-Tetra(3-methylphenyl) porphine(50849-45-1)

Safety Data

• Hazardous Substances Data: 50849-45-1(Hazardous Substances Data)

Usage

Uses

Used in Photochemistry Research:
meso-Tetra(3-methylphenyl) porphine is used as a key compound in photochemistry research for its ability to interact with light and participate in various photochemical reactions. Its unique structure and properties make it a valuable tool for studying the behavior of molecules under light exposure.
Used in Biological Sciences:
meso-Tetra(3-methylphenyl) porphine is used as a model compound in biological sciences to understand the structure and function of heme proteins and other biological systems that contain porphyrins. Its nitrogen centers and potential binding capabilities to various metals make it a useful tool for investigating the interactions between porphyrins and metal ions in biological processes.
Used in Materials Sciences:
meso-Tetra(3-methylphenyl) porphine is used as a building block in materials sciences for the development of new materials with unique properties. Its ability to bind to metals and other molecules can be exploited to create materials with potential applications in areas such as catalysis, sensing, and energy storage.

Upstream product

• 109-97-7 pyrrole 
• 620-23-5 m-tolyl aldehyde 
• 101-60-0 porphyrin 

Downstream Products

• 82265-76-7 Co(TTP) 
• 118517-73-0 [5,10,15,20-tetrakis(3-methylphenyl)porphyrinato]copper(II) 
• 119695-93-1 5-(3-methyl-4-nitrophenyl)-10,15,20-tris(3-methylphenyl)porphyrin 

Relevant articles and documents

A novel, high-yielding synthesis of meso-substituted porphyrins via the direct arylation of porphine

A new method for the synthesis of meso-substituted porphyrins is described: reaction of 5,10,15,20-tetrabromoporphine magnesium complex with aryl or heteroaryl boronic acids in the presence of Pd(PPh3)4 gave meso-substituted porphyri

A four-phenyl porphine preparation method

The invention discloses a preparation method of meso-tetraphenylchlorin. The preparation method comprises the steps that 1, a mixed solution of pyrrole and aromatic aldehyde is prepared for standby; 2, a solvent is added into a polymerization reactor, nitrogen displacement is conducted till the concentration of tail oxygen is lower than 1%, the solvent is heated to backflow, the mixed solution obtained in the first step starts to be dropwise added, a reaction is started, after the mixed solution is dropwise added completely, the reaction is continuously conducted for 0.05 h to 0.5 h, and then the reaction is stopped; 3, oxygen-containing gas with the oxygen volume fraction ranging from 5% to 100% is fed into the polymerization reactor for oxidation, cooling is conducted after the oxidation is completed, filtration is conducted to obtain a filter cake and filtrate, and a product is obtained after the filter cake is washed and dried. The preparation method of the meso-tetraphenylchlorin has the advantages that the yield is high, safety and environmental protection are achieved, separation and purification are easy, and the product quality is stable.

A four-phenyl porphine production method (by machine translation)

The invention discloses a production method for tetraphenyl porphin. The production method includes the steps that 1, pyrrole and aromatic aldehyde are prepared into a mixed solution for standby application; 2, solvent is added into a polymerization reactor, the pressure of the polymerization reactor is maintained at 1-5 atm, the mixed solution obtained in the step 1 starts to be dripped to start a polymerization reaction, after the reaction is finished, reaction products are cooled to normal temperature, and filter liquor and a filter cake are obtained through filtration; 3, the filter cake obtained in the step 2 and propionic acid are added into an oxidation reactor, oxygen-containing gas is introduced to carry out an oxidation reaction, cooling is carried out after oxidation is finished, a solid and filter liquor are obtained through filtration, and the solid is washed and dried to obtain the tetraphenyl porphin. The production method has the advantages of being high in yield, safe and environmentally friendly, separation and purification are easy, and the production quality is stable.

Synthetic method of porphyrin and porphyrin derivative

The invention discloses a synthetic method of porphyrin and a porphyrin derivative. According to the method, a reaction separation synchronous reactor is used to prepare porphyrin and the porphyrin derivative. The reaction separation synchronous reactor includes a stirring reaction tower and a constant-temperature settlement tower connected to the bottom of the stirring reaction tower. The method comprises: adding a mixed raw material of pyrrole, a benzaldehydes compound, organic carboxylic acid and DMF in the reaction separation synchronous reactor till the reaction zone of the constant-temperature settlement tower and the stirring reaction tower is filled with the mixed raw material, controlling the temperature in the stirring reaction tower in a range of 130-155 DEG C and controlling the temperature of the constant-temperature settlement tower in a range of 50-80 DEG C, and obtaining the porphyrin or porphyrin derivative precipitation from the constant-temperature settlement tower. According to the method, no complicated separation means is adopted, and high-purity porphyrin is obtained at a high yield. The method allows industrial production to be easily achieved.

Efficient synthesis of meso-tetraarylporphyrins using i2 as catalyst and ibx as oxidant

meso-Tetraarylporphyrins are synthesized from pyrrole and substituted benzaldehydes by a catalytic amount of I2 as catalyst and o-iodoxybenzoic acid (IBX) as oxidant in two steps and one flask. The advantages of this method include the use of inexpensive and easily available catalyst, avoidance of heavy consumption of CH2Cl2, innocuous oxidant, and good yields.

Novel synthesis of meso-tetraarylporphyrins by using I2 as catalyst and air as oxidant under thermal or UV conditions

An efficient and novel synthesis of meso-tetraarylporphyrins is accomplished through iodine-catalyzed condensation of pyrrole, and aryl aldehydes and subsequent oxidation by air under thermal or ultraviolet (UV) irradiation conditions. The advantages of this procedure include good yields and a green nature. Copyright

Novel synthesis of meso-tetraarylporphyrins using CF3SO 2Cl under aerobic oxidation

meso-Tetraarylporphyrins are synthesized from pyrrole and aryl aldehydes cleanly and efficiently in one pot at room temperature using equimolar amount of CF3SO2Cl in the presence of air as oxidant. By this novel method 5,10,15,20-tetraarylporphyrins can be prepared in excellent yields.

Phosphorus pentachloride (PCl5) mediated synthesis of tetraarylporphyrins

A new synthesis of porphyrins from pyrrole and substituted benzaldehydes is described, with PCl5 as catalyst. Aromatic aldehydes condense irreversibly with pyrrole in the presence of this catalyst, and aerobic oxidation of porphyrinogen provides functionalized porphyrins in yields of 20-65%.

Synthesis of meso-tetraarylporphyrins in air with silica chloride as catalyst

Meso-tetraarylporphyrins (14 examples) are prepared efficiently by condensation of pyrrole with aromatic aldehydes in the presence of silica chloride, followed by air oxidation. The method is compared with other published procedures.

Preparation of meso-Tetraarylporphyrins Nitrated in Two Neighboring Aromatic Rings

Selective nitration of tetraphenylporphyrin (TPP) and its derivatives is reported. The reaction of meso-aryl substituted porphyrins with fuming yellow nitric acid (d = 1.53) at the temperature 0-20°C results in the formation of 5,10-bis(4-nitroaryl)-15,20