50868-35-4 Usage
Description
(2β,5α,12β,19α)-6,7-Didehydroaspidospermidine-3β-carboxylic acid methyl ester is a chemical compound belonging to the class of aspidosperma alkaloids, derived from Aspidosperma plants. It features a unique chemical structure and exhibits potential pharmacological activities, such as anticancer and antimalarial properties. The methyl ester form of this compound enhances its stability and bioavailability, making it a promising candidate for the development of new pharmaceutical drugs.
Uses
Used in Pharmaceutical Industry:
(2β,5α,12β,19α)-6,7-Didehydroaspidospermidine-3β-carboxylic acid methyl ester is used as a pharmaceutical candidate for its potential anticancer and antimalarial properties. Its unique chemical structure and enhanced stability due to the methyl ester form make it valuable for further research and development of new drugs to treat various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 50868-35-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,8,6 and 8 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 50868-35:
(7*5)+(6*0)+(5*8)+(4*6)+(3*8)+(2*3)+(1*5)=134
134 % 10 = 4
So 50868-35-4 is a valid CAS Registry Number.
50868-35-4Relevant articles and documents
SYNTHESIS AND NMR-STUDY OF EPIMERIC PAIRS OF 2,3-DIHYDRO- AND 2,3,6,7-TETRAHYDROTABERSONINE AND THEIR DERIVATIVES
Zsadon, B.,Balogh, Emilia R.,Kassay, Viktoria B.,Sohar, P.,Csampai, A.
, p. 183 - 192 (2007/10/02)
The biologically prospective 2βH,3βH- and 2βH,3αH-derivatives of tabersonine 1, (-)-vincadifformine (6,7-dihydro-tabersonine) 2 as well as their 15-nitro and 15-bromo substituted analogues were synthesized by a modified regioselective method with zinc.Most of the products 3a,b-8a,b are new alkaloid derivatives which have special importance in pharmacological applications.According to their 1H and 13C NMR investigations including differential nuclear Overhauser effect (DNOE) measurements, in contrast to the conclusions published earlier, ring C has boat form carrying equatorial 3α-COOMe group in the 2βH,3βH derivatives, whereas in the 2βH,3αH epimers ring C has their conformation with equatorially positioned 3β-COOMe group on it.
