50886-83-4

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 708-06-5 2-hydroxynaphthalene-1-carbaldehyde 
• 148642-24-4 1-((pyrimidine-2-ylimino)methyl)naphthalene-2-ol 
• 135-19-3 β-naphthol 

Downstream Products

• 191332-67-9 diphenyl[N,N'-bis(2-hydroxy-1-naphthaldehyde)-1,2-phenylenediiminato]tin(IV) 

Relevant academic research and scientific papers

In situ alkaline media: Synthesis, spectroscopic, morphology and anticancer assignments of some transition metal ion complexes of 1-((2-aminophenylimino) methyl) naphthalen-2-ol Schiff base

Four Schiff base complexes of Cu(II), Co(II), Ni(II) and Zn(II) metal ions were synthesized by reaction of 1-((2-aminophenylimino)methyl)naphthalen-2-ol (HL) with metal(II) chloride salts. The geometric structures of these complexes were elucidated based

Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some Schiff's bases

A series of N-(acridin-9-yl)-4-(benzo[d]imidazol/oxazol-2-yl) benzamides has been synthesized by the condensation of 9-aminoacridine derivatives with benzimidazole or benzoxazole derivatives. Condensation of 2-hydroxy naphthaldehyde with functionalized di

Double-decker luminescent ytterbium and erbium SMMs with symmetric and asymmetric Schiff base ligands

Multifunctional molecules that respond both to magnetic fields and light are subject of study due to possible applications in fields as diverse as imaging or information processing and storage. In this paper we report visible and NIR emitting single-molec

A simple turn-on Schiff base fluorescence sensor for aluminum ion

A simple Schiff base L derived from 2-hydroxy-naphthalene-1-carbaldehyde and benzene-1,2-diamine, was proved to be a turn-on fluorescent probe for the recognition of Al3+, based on photoinduced electron transfer (PET) mechanism. It exhibited a

Zn(II), Ni(II), Cu(II) and Pb(II) complexes of tridentate asymmetrical Schiff base ligands: Synthesis, characterization, properties and biological activity

New asymmetrical tridentate Schiff base ligands were synthesized using 1,2-phenylenediamine, 4-methyl-1,2-phenylenediamine, 2-hydroxy-1-napthaldehyde, 9-anthracenecarboxaldehyde. Schiff base ligands and their metal complexes were synthesised and character

COLORANT COMPOSITION, PHOTOSENSITIVE RESIN COMPOSITION, PHOTO RESIST, COLOR FILTER, AND DISPLAY DEVICE

The present invention relates to a color material composition comprising a compound represented by chemical formula 1, a photosensitive resin composition comprising the same, a photosensitive material, a color filter, and a display device. The color mater

Efficacy of novel schiff base derivatives as antifungal compounds in combination with approved drugs against candida albicans

Background: The increasing incidence of fungal infections, especially caused by Candida albicans, and their increasing drug resistance has drastically increased in recent years. Therefore, not only new drugs but also alternative treatment strategies are promptly required. Methods: We previously reported on the synergistic interaction of some azole and non-azole compounds with fluconazole for combination antifungal therapy. In this study, we synthesized some non-azole Schiff-base derivatives and evaluated their antifungal activity profile alone and in combination with the most commonly used antifungal drugs-fluconazole (FLC) and amphotericin B (AmB) against four drug susceptible, three FLC resistant and three AmB resistant clinically isolated Candida albicans strains. To further analyze the mechanism of antifungal action of these compounds, we quantified total sterol contents in FLC-susceptible and resistant C. albicans isolates. Results: A pyrimidine ring-containing derivative SB5 showed the most potent antifungal activity against all the tested strains. After combining these compounds with FLC and AmB, 76% combinations were either synergistic or additive while as the rest of the combinations were indifferent. Interestingly, none of the combinations was antagonistic, either with FLC or AmB. Results interpreted from fractional inhibitory concentration index (FICI) and isobolograms revealed 4-10-fold reduction in MIC values for synergistic combinations. These compounds also inhibit ergosterol biosynthesis in a concentration-dependent manner, supported by the results from docking studies. Conclusion: The results of the studies conducted advocate the potential of these compounds as new antifungal drugs. However, further studies are required to understand the other mechanisms and in vivo efficacy and toxicity of these compounds.

A novel approach toward the synthesis of some new tridentate Schiff bases from anil-like compounds

A novel method was developed for synthesizing a series of new tridentate Schiff base ligands starting from hydroxynaphthyl pyrimidinyl amines with o-phenylenediamines or o-aminophenol or 2-amino-3-hydroxy-pyridine in the presence of formic acid catalyst under solvent-free conditions. In these reactions [1+1], the condensation product as half-unit ligand was obtained. Moreover, the reaction of hydroxynaphthylmethylene pyrimidinyl amines with 3,4-diaminopyridine and 1,8-naphthalenediamine leads to the formation of C2-naphthylated imidazopyridine and dihydropyrimidine, respectively. The attractive features of this protocol are use of an inexpensive catalyst, operational simplicity, short reaction times, easy handling, and good yields.

Triple-signaling mechanisms-based three-in-one multi-channel chemosensor for discriminating Cu2+, acetate and ion pair mimicking AND, NOR, INH and IMP logic functions

Chemosensor 1 shows three different responses towards Cu2+, acetate and Cu(OAc)2 ion pair at different wavelengths independently in its absorption and fluorescence behaviour following a triple-signaling mechanism, namely, internal ch