50887-69-9

Basic information

• Product Name: OROTIC ACID MONOHYDRATE
• Synonyms: 1,2,3,6-TETRAHYDRO-2,6-DIOXO-4-PYRIMIDINECARBOXYLIC ACID, HYDRATE;2,6-DIOXO-1,2,3,6-TETRAHYDRO-4-PYRIMIDINECARBOXYLIC ACID HYDRATE;2,6-DIOXO-1,2,3,6-TETRAHYDRO-4-PYRIMIDINECARBOXYLIC ACID MONOHYDRATE;2,4-DIHYDROXYPYRIMIDINE-6-CARBOXYLIC ACID HYDRATE;2.4-DIHYDROXYPYRIMIDINE-6-CARBOXYLIC ACID MONOHYDRATE;6-URACILCARBOXYLIC ACID, HYDRATE;OROTIC ACID HYDRATE;OROTIC ACID MONOHYDRATE
• CAS NO: 50887-69-9
• Molecular Formula: C5H6N2O5
• Molecular Weight: 174.11
• EINECS: 200-619-8
• Product Categories: Miscellaneous Natural Products;Heterocyclic Compounds;Biochemistry;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;Building Blocks;C4 to C5;Chemical Synthesis;Heterocyclic Building Blocks;Nutrition Research;Other Biochemical;Phytochemicals by Chemical Classification;Pyrimidines;pharmaceutical
• Mol File: 50887-69-9.mol
• Article Data: 0

Chemical Properties

• Melting Point: >300 °C(lit.)
• Boiling Point: 431.3 °C at 760 mmHg
• Flash Point: 214.6 °C
• Appearance: White to off-white/Crystalline Powder
• Density: 1.642 g/cm3
• Vapor Pressure: 7.6E-09mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Aqueous Base (Slightly), DMSO (Slightly)
• Water Solubility: Soluble in water (1.7 mg/ml), and ammonium hydroxide. Insoluble in chloroform.
• Merck: 14,6876
• BRN: 383901
• CAS DataBase Reference: OROTIC ACID MONOHYDRATE(CAS DataBase Reference)
• NIST Chemistry Reference: OROTIC ACID MONOHYDRATE(50887-69-9)
• EPA Substance Registry System: OROTIC ACID MONOHYDRATE(50887-69-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: RM3180000
• TSCA: Yes
• Hazardous Substances Data: 50887-69-9(Hazardous Substances Data)

Usage

Chemical Properties

white to off-white crystalline powder

Uses

Different sources of media describe the Uses of 50887-69-9 differently. You can refer to the following data:
1. Orotic Acid is used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment.
2. Orotic acid hydrate is used in cosmetic and food industry. It is also used as a pharmaceutical intermediate.

Purification Methods

It crystallises from water. The anhydrous acid [65-86-1] M 156.1 has m 245-246o(dec). [Nye & Mitchell J Am Chem Soc 69 1382 1947, Beilstein 25 III/IV 1759.]

InChI:InChI=1/C5H4N2O4.H2O/c8-3-1-2(4(9)10)6-5(11)7-3;/h1H,(H,9,10)(H2,6,7,8,11);1H2