50892-42-7Relevant academic research and scientific papers
Compounds, compositions and methods for modulating beta-amyloid production
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, (2008/06/13)
Methods and compositions useful in the treatment of amyloidosis and conditions and diseases associated therewith, such as Alzheimer's disease, are provided. The methods involve administering to a subject in need thereof a pharmaceutical composition including one or more agents that modulate PPARα and/or PPARδ activity, resulting in an inhibition of β-amyloid production and/or release from cells of the subject, particularly brain cells.
Compounds, compositions and methods for modulating beta-amyloid production
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, (2008/06/13)
Methods and compositions useful in the treatment of amyloidosis and conditions and diseases associated therewith, such as Alzheimer's disease, are provided. The methods involve administering to a subject in need thereof a pharmaceutical composition includ
2-PYRIMIDINYLTHIO)ALKANOIC ACIDS, ESTERS, AMIDES AND HYDRAZIDES
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, (2008/06/13)
(2-Pyrimidinylthio)alkanoic acid, esters, amides and hydrazides as well as various 4- and 6-substituted derivatives thereof as depicted by the structural formula: SPC1 In which R and R2 are independently --H or lower alkyl; R1 is --H
