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Z-Asn-OPfp, also known as O-(2,4,6-trimethylbenzenesulfonyl)-L-asparagine, is a chemical compound that serves as a protected amino acid derivative. It is used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), to protect the side chain of asparagine (Asn) from unwanted reactions. The compound features a 2,4,6-trimethylbenzenesulfonyl (Tosyl) group, which is a commonly used protecting group for the amide nitrogen in asparagine. This protection is crucial to prevent side reactions during peptide bond formation, ensuring the correct sequence and structure of the synthesized peptide. Z-Asn-OPfp is a valuable tool in the field of biochemistry and pharmaceuticals, enabling the creation of complex peptide sequences with high precision.

50903-73-6

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50903-73-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 50903-73-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,9,0 and 3 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 50903-73:
(7*5)+(6*0)+(5*9)+(4*0)+(3*3)+(2*7)+(1*3)=106
106 % 10 = 6
So 50903-73-6 is a valid CAS Registry Number.

50903-73-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name Z-Asn-OPfp

1.2 Other means of identification

Product number -
Other names N-Benzyloxy-carbonyl-L-asparaginpentafluorphenylester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:50903-73-6 SDS

50903-73-6Relevant academic research and scientific papers

Synthesis of the HIV-proteinase inhibitor Saquinavir: A challenge for process research

G?hring, Wolfgang,Gokhale, Surendra,Hilpert, Hans,Roessler, Felix,Schlageter, Markus,Vogt, Peter

, p. 532 - 537 (2007/10/03)

The task of process research, namely developing efficient, economically and technically as well as ecologically feasible syntheses in time, is demonstrated on the HIV-proteinase inhibitor Saquinavir (1), a complex molecule comprising six stereo-centres. Based on the first 26-step research synthesis furnishing a 10% overall yield, process research established a new, short 11-step synthesis affording a 50% overall yield.

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