50906-61-1

Upstream product

• 316187-65-2 (2E,4E,6E,8E/Z,10E,12E)-12-hydroxy-14-[(1R,4S)-4-hydroxy-1,2,2-trimethylcyclopentyl]-2,7,11-trimethyl-14-oxotetradeca-2,4,6,8,10,12-hexaenal 
• 245504-00-1 [(4R)-4-tert-butyldimethylsilyloxy-2,6,6-trimethylcyclohex-1-enyl]acetaldehyde 
• 408357-89-1 2-[(4R)-4-tert-butyldimethylsilyloxy-2,6,6-trimethylcyclohex-1-enyl]ethanol 
• 314774-14-6 (2E,4E)-4-acetyloxy-6-[(1R,4S)-4-hydroxy-1,2,2-trimethylcyclopentyl]-3-methyl-6-oxohexa-2,4-dienal 
• 314774-15-7 2-[(4R)-4-tert-butyldimethylsilyloxy-2,6,6,-trimethylcyclohex-1-enyl]ethyl acetate 
• 314774-12-4 2-[(1S,4S,6R)-4-tert-butyldimethylsilyloxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptan-1-yl]ethyl acetate 
• 314774-13-5 Acetic acid 3-[(1R,4S)-4-(tert-butyl-dimethyl-silanyloxy)-1,2,2-trimethyl-cyclopentyl]-3-oxo-propyl ester 
• 473670-92-7 Acetic acid 3-[(1R,4S)-4-(tert-butyl-dimethyl-silanyloxy)-1,2,2-trimethyl-cyclopentyl]-3-hydroxy-propyl ester 
• 314774-17-9 3-[(1R,4S)-4-tert-butyldimethylsilyloxy-1,2,2-trimethylcyclopentyl]-3-{[(4-methoxyphenyl)methoxy]methoxy}propanal 
• 473670-95-0 Acetic acid (E)-1-[2-[(1R,4S)-4-(tert-butyl-dimethyl-silanyloxy)-1,2,2-trimethyl-cyclopentyl]-2-oxo-eth-(Z)-ylidene]-2-methyl-4-oxo-but-2-enyl ester 
• 473670-89-2 3-[(1R,4S)-4-tert-butyldimethylsilyloxy-1,2,2-trimethylcyclopentyl]-3-{[(4-methoxyphenyl)methoxy]methoxy}propan-1-ol 
• 473670-91-6 (2E,4E)-3-acetyloxy-1-[(1R,4S)-4-tert-butyldimethylsilyloxy-1,2,2-trimethylcyclopentyl]-6-hydroxy-4-methylhexa-2,4-dienone 
• 314774-16-8 3-[(1R,4S)-4-tert-butyldimethylsilyloxy-1,2,2-trimethylcyclopentyl]-3-{[(4-methoxyphenyl)methoxy]methoxy}propyl acetate 
• 314774-19-1 (4E)-6-tert-butyldimethylsilyloxy-1-[(1R,4S)-4-tert-butyldimethylsilyloxy-1,2,2-trimethylcyclopentyl]-1-hydroxy-4-methylhex-4-en-3-one 

Downstream Products

• 52049-47-5 mytiloxanthin diacetate 

Relevant academic research and scientific papers

Anti-oxidative activity of mytiloxanthin, a metabolite of fucoxanthin in shellfish and tunicates

Anti-oxidative activities of mytiloxanthin, a metabolite of fucoxanthin in shellfish and tunicates, were investigated. Mytiloxanthin showed almost the same activities for quenching singlet oxygen and the inhibition of lipid peroxidation as those of astaxanthin, which is a well-known singlet oxygen quencher. Furthermore, mytiloxanthin showed excellent scavenging activity for hydroxyl radicals and this activity was markedly higher than that of astaxanthin.

Carotenoids and related polyenes. Part 8. Total synthesis of optically active mytiloxanthin applying the stereoselective rearrangement of tetrasubstituted epoxide

Biomimetic synthesis of mytiloxanthin 1 was accomplished with stereoselective rearrangement of the tetrasubstituted epoxide 5 as a key reaction. This is the first total synthesis of optically active all-E mytiloxanthin 1.

First total synthesis of mytiloxanthin

The first total synthesis of mytiloxanthin 2 was accomplished via the cyclopentyl ketone 7 prepared by stereoselective rearrangement of the epoxide 4a.