509151-97-7

Basic information

• Product Name: Ethanol, 2-[(2-fluoro-4-nitrophenyl)amino]- (9CI)
• Synonyms: 2-Fluoro-N-(2-hydroxyethyl)-4-nitroaniline;Ethanol, 2-[(2-fluoro-4-nitrophenyl)amino]- (9CI);2-FLUORO-N-(2-HYDROXYETHYL)-4-NITROANILINE(WXC06358)
• CAS NO: 509151-97-7
• Molecular Formula: C8H9FN2O3
• Molecular Weight: 200.1670632
• Product Categories: FLUORO
• Mol File: 509151-97-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 381.2±37.0 °C(Predicted)
• Appearance: /
• Density: 1.440±0.06 g/cm3(Predicted)
• PKA: 14.51±0.10(Predicted)
• CAS DataBase Reference: Ethanol, 2-[(2-fluoro-4-nitrophenyl)amino]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanol, 2-[(2-fluoro-4-nitrophenyl)amino]- (9CI)(509151-97-7)
• EPA Substance Registry System: Ethanol, 2-[(2-fluoro-4-nitrophenyl)amino]- (9CI)(509151-97-7)

Safety Data

• Hazardous Substances Data: 509151-97-7(Hazardous Substances Data)

Usage

Uses

2-[(2-Fluoro-4-nitrophenyl)amino]ethan-1-ol is a chemical reagent used in the synthesis of oxazolidinone compounds as antibiotics and other anti-bacterial agents.

Upstream product

• 369-34-6 3,4-difluoronitrobenzene 
• 141-43-5 ethanolamine 
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Relevant articles and documents

METHOD FOR PREPARING (R)-3-(3-FLUORO-4-(1-METHYL-5,6-DIHYDRO-1,2,4-TRIAZIN-4(1H)-YL)PHENYL)-5-(SUBSTITUTED METHYL)OXAZOLIDIN-2-ONE DERIVATIVES

Provided are a method for preparing (R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(substituted methyl)oxazolidin-2-one derivatives, which are oxazolidinone antibiotic compounds having a cyclic amidrazone group, represented by Chemical Formula 1, and intermediates thereof, and uses 3,4-difluoro-4-nitrobenzen as a starting material. According to the preparation method of the present invention, (R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(substituted methyl)oxazolidin-2-one derivatives, which are useful as oxazolidinone antibiotics, can be prepared in high purity and high yield in a simpler manner than conventional methods.

NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES

The present invention provides PI3K protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorders with them.

Observation of O→N type smiles rearrangement in certain alkyl aryl nitro compounds

Smiles rearrangements on some alkyl aryl nitro compounds having NH2 group as the nucleophile and oxygen as the leaving group are reported.