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1-(2-chloroethyl)-3-(2-fluoroethyl)-1-nitrosourea, commonly known as lomustine, is a nitrosourea alkylating agent with potent antineoplastic properties. It is characterized by its ability to disrupt DNA synthesis and repair mechanisms in cancer cells, leading to cell death. Lomustine is typically administered orally and has a long half-life, which contributes to its convenience in dosing and effectiveness in eradicating cancer cells.

50922-87-7

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50922-87-7 Usage

Uses

Used in Oncology:
Lomustine is utilized as a chemotherapeutic agent for the treatment of various types of brain tumors, lymphomas, and other forms of cancer. Its mechanism of action involves the interference with DNA synthesis and repair processes in cancer cells, which ultimately results in cell death. However, due to its potential toxic effects on normal tissues, it can cause side effects such as bone marrow suppression, lung toxicity, and liver damage. As a result, the use of lomustine requires close monitoring and management by medical professionals to ensure patient safety and therapeutic efficacy.
Used in Pharmaceutical Research and Development:
In the field of pharmaceutical research and development, lomustine serves as a valuable compound for the investigation of new cancer treatment strategies. Its alkylating properties and impact on DNA synthesis make it a key component in the development of novel antineoplastic drugs and drug combinations that aim to improve patient outcomes and reduce side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 50922-87-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,9,2 and 2 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 50922-87:
(7*5)+(6*0)+(5*9)+(4*2)+(3*2)+(2*8)+(1*7)=117
117 % 10 = 7
So 50922-87-7 is a valid CAS Registry Number.

50922-87-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-chloroethyl)-3-(2-fluoroethyl)-1-nitrosourea

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:50922-87-7 SDS

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