5093-91-4Relevant academic research and scientific papers
Composition for the delivery of a pharmaceutical agent to a patient
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, (2008/06/13)
The present invention relates to a composition for the delivery of a pharmaceutical agent to a patient that comprises polyethylene glycol, an aqueous solution containing polyvinylpyrrolidone, and a pharmaceutical agent. The invention also relates to methods of making a composition for the delivery of a pharmaceutical agent.
Encapsulation of microparticles in teardrop shaped polymer capsules of cellular size
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, (2008/06/13)
Microparticles such as propagules of eukaryotic biocontrol agents are encapsulated in cellular-scale polymer capsules that have a diameter similar to normal eukaryotic cells in a range of about 10 μm to about 400 μm. The microparticles are encapsulated by adding a hydrophobic dispersion medium such as a mixture of chloroform and hexane or a mixture of corn oil and n-hexadecane having a specific gravity of about 1 and containing an emulsifier such as lecithin to an aqueous suspension of the microparticles and a polymer matrix precursor such as alginate, agitating vigorously to form a stable emulsion of microscopic globules containing a microparticle, and adding the emulsion to an aqueous solution containing a polymerizing agent such as calcium chloride to polymerize and precipitate the globules to form microparticles encapsulated in polymer matrix capsules that may be of a teardrop shape having a length of 40-200% longer than the diameter. Precipitation of the globules is regulated by substantially matching the Specific Gravity of the hydrophobic dispersion medium and the aqueous suspension. The microparticle may be a viable propagule of a weed pathogenic fungus to provide a herbicidal composition.
N-alkyl-lactams as crystallization inhibitors
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, (2008/06/13)
In the spraying of an aqueous liquor comprising at least one of 1-(4-chlorophenyl)-4,4-dimethyl-3-(1,2,4-triazol-1-yl-methyl)-pentan-3-ol and 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)-butan-2-ol, the improvement which comprises including in the liquor an N-alkyl-lactam of the formula STR1 in which R represents alkyl having 8 to 18 carbon atoms and n represents the numbers 3, 4 or 5,
Self-emulsifiable dermatologic cream
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, (2008/06/13)
The cream comprises a mixture of sorbitan monosteaerate, polyoxyethylenated sorbitan monostearate, steraric acid, petrolatum oil, isopropryl myristate, triethanolamine, methyl parahydroxybenzoate, propyl parahydroxybenzoate, water (distilled or natural). The mixture is heated until the products are all melted and solubilized, and brought to a temperature between 80° C. and 120° C., for a period of time of 15 to 75 minutes. The mixture is then stirred while being left to cool down.
