50963-77-4

Basic information

• Product Name: 2-(3-aminophenoxy)-1-ethanol
• Synonyms: 2-(3-aminophenoxy)-1-ethanol;2-(3-aminophenoxy)ethanol(SALTDATA: FREE);3-(2-Hydroxyethoxy)aniline
• CAS NO: 50963-77-4
• Molecular Formula: C₈H₁₁NO₂
• Molecular Weight: 153.18
• Mol File: 50963-77-4.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 333.9°C at 760 mmHg
• Flash Point: 155.7°C
• Appearance: /
• Density: 1.18g/cm³
• Vapor Pressure: 5.24E-05mmHg at 25°C
• Refractive Index: 1.582
• CAS DataBase Reference: 2-(3-aminophenoxy)-1-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-aminophenoxy)-1-ethanol(50963-77-4)
• EPA Substance Registry System: 2-(3-aminophenoxy)-1-ethanol(50963-77-4)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 50963-77-4(Hazardous Substances Data)

Usage

General Description

2-(3-aminophenoxy)-1-ethanol, also known as APE, is a chemical compound that contains a phenol group and an amine group attached to an ethanol molecule. It is often used as a chemical intermediate in the production of various pharmaceuticals, agrochemicals, and dyes. APE is also used as a corrosion inhibitor and as an intermediate in the synthesis of surfactants and other specialty chemicals. It is a colorless to pale yellow liquid with a slightly sweet odor and is soluble in water, making it a versatile and widely used chemical in various industrial applications. However, it is important to handle APE with caution, as it can be harmful if swallowed, inhaled, or in contact with skin and eyes.

InChI:InChI=1/C8H11NO2/c9-7-2-1-3-8(6-7)11-5-4-10/h1-3,6,10H,4-5,9H2

Upstream product

• 16365-26-7 2-(3-nitrophenoxy)ethanol 
• 58559-52-7 3-aminophenoxyacetic acid ethyl ester 
• 5544-77-4 2-(3-nitrophenoxy)-acetic acid ethyl ester 
• 1448309-95-2 N-(4,4-difluorocyclohexyl)formamide 
• 96042-30-7 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran 
• 554-84-7 meta-nitrophenol 

Downstream Products

• 860518-06-5 [3-(2-hydroxy-ethoxy)-phenyl]-arsonic acid 
• 920946-30-1 1-benzyl-3-[3-(2-hydroxyethoxy)phenylamino]pyrrole-2,5-dione 
• 857578-88-2 [3-(2-hydroxy-ethoxy)-2-nitro-phenyl]-arsonic acid 
• 857578-87-1 [3-(2-hydroxy-ethoxy)-4-nitro-phenyl]-arsonic acid 
• 854228-49-2 2-(5-arsenoso-2-nitro-phenoxy)-ethanol 
• 854228-50-5 2-(3-arsenoso-2-nitro-phenoxy)-ethanol 
• 857628-58-1 (3-hydroxy-2-nitro-phenyl)-arsonic acid 
• 860517-82-4 (3-hydroxy-4-nitro-phenyl)-arsonic acid 

Relevant articles and documents

Copper nanoparticles (CuNPs) catalyzed chemoselective reduction of nitroarenes in aqueous medium

Abstract: A procedure for practical synthesis of CuNPs from CuSO4·5H2O is established, under appropriate reaction conditions, using rice (Oryza sativa) as an economic source of reducing as well as a stabilizing agent. Optical and microscopic techniques are employed for the characterization of the synthesized CuNPs and the sizes of the particles were found to be in the range of 8 ± 2 nm. The nanoparticles are used as a catalyst for chemoselective reduction of aromatic nitro compounds to corresponding amines under ambient conditions and water as a reaction medium. Graphic abstract: CuNPs are synthesized using hydrolysed rice and used as catalyst for chemoselective reduction of nitroarenes to their corresponding amines in water. [Figure not available: see fulltext.]

THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE

Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.

THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE

Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.