50994-51-9

Basic information

• Product Name: N-(4-hydroxyphenyl)-4-nitrobenzenesulfonamide
• Synonyms: benzenesulfonamide, N-(4-hydroxyphenyl)-4-nitro-; N-(4-Hydroxy-phenyl)-4-nitro-benzenesulfonamide
• CAS NO: 50994-51-9
• Molecular Formula: C₁₂H₁₀N₂O₅S
• Molecular Weight: 294.2832
• Mol File: 50994-51-9.mol

Chemical Properties

• Boiling Point: 522.7°C at 760 mmHg
• Flash Point: 269.9°C
• Density: 1.558g/cm³
• Vapor Pressure: 1.52E-11mmHg at 25°C
• Refractive Index: 1.681
• CAS DataBase Reference: N-(4-hydroxyphenyl)-4-nitrobenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-hydroxyphenyl)-4-nitrobenzenesulfonamide(50994-51-9)
• EPA Substance Registry System: N-(4-hydroxyphenyl)-4-nitrobenzenesulfonamide(50994-51-9)

Safety Data

• Hazardous Substances Data: 50994-51-9(Hazardous Substances Data)

Upstream product

• 123-30-8 4-amino-phenol 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 51-78-5 p-aminophenol hydrochloride 
• 1441409-91-1 (E)-ethyl 2-cyano-2-(4-nitrophenylsulfonyloxyimino)acetate 
• 113591-42-7 4-nitro-N-(4-oxocyclohexa-2,5-dien-1-ylidene)benzenesulfonamide 

Downstream Products

• 1489231-08-4 N-(3-((7H-purin-6-yl)thio)-4-hydroxyphenyl)-4-nitrobenzenesulfonamide 
• 113591-42-7 4-nitro-N-(4-oxocyclohexa-2,5-dien-1-ylidene)benzenesulfonamide 
• 1489231-01-7 N-(3-((1H-1,2,4-triazol-5-yl)thio)-4-hydroxyphenyl)-4-nitrobenzenesulfonamide 
• 1489231-03-9 N-(4-hydroxy-3-((5-methyl-1,3,4-thiadiazol-2-yl)thio)phenyl)-4-nitrobenzenesulfonamide 
• 1489231-04-0 N-(3-((1,3,4-thiadiazol-2-yl)thio)-4-hydroxyphenyl)-4-nitrobenzenesulfonamide 
• 1489231-06-2 N-(4-hydroxy-3-((1-methyl-1H-tetrazol-5-yl)thio)phenyl)-4-nitrobenzenesulfonamide 

Relevant articles and documents

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By employing triethylamine as a catalyst, [3?+?2] coupling-elimination cascade of α,α-dicyanoolefins with quinone monoimines was realized. The reactions afforded various novel pterocarpen analogues with generally moderate yields (up to 75%). In addition, a plausible reaction mechanism was proposed.

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A highly enantioselective arylation of 3-carboxamide oxoindoles with quinone monoimines is described. Various 3-aryl-3-carboxamide oxindoles with an all-carbon quaternary center were obtained in moderate to good yields (up to 99%) with moderate to good enantioselectivities (up to 98%) in the presence of a bifunctional thiourea-tertiary amine catalyst. The absolute configuration of one product was determined by an X-ray crystal structural analysis and the absolute configurations of the other products can be assigned by analogy. Moreover, several chiral spirooxindole-benzofuranones were synthesized from the 3-aryl-3-carboxamide oxindoles in moderate yields with moderate to good enantioselectivities.

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