50998-05-5

Usage

Uses

Used in Pharmaceutical Synthesis:
4-(2-aminopropyl)morpholine is used as an intermediate in the synthesis of pharmaceuticals for its ability to facilitate the creation of complex organic compounds, contributing to the development of new drugs.
Used in Agrochemical Production:
In the agrochemical industry, 4-(2-aminopropyl)morpholine serves as an intermediate, aiding in the production of various agrochemicals that are essential for crop protection and enhancement of agricultural yields.
Used as a Corrosion Inhibitor in Industrial Applications:
4-(2-aminopropyl)morpholine is utilized as a corrosion inhibitor, protecting materials from degradation in industrial settings, thereby extending the lifespan of equipment and structures.
Used in Chemical Processes and Formulations:
Due to its stabilizing and chelating properties, 4-(2-aminopropyl)morpholine is employed in various chemical processes to ensure the stability and effectiveness of formulations, enhancing the performance of end products.
It is crucial to handle 4-(2-aminopropyl)morpholine with care, considering its potential hazards and adverse effects if not used properly, ensuring safety in all applications.

InChI:InChI=1/C7H16N2O/c1-7(8)6-9-2-4-10-5-3-9/h7H,2-6,8H2,1H3

Upstream product

• 110-91-8 morpholine 
• 2403-31-8 2-amino-1-bromopropane hydrobromide 
• 100958-20-1 N-(β-morpholino-isopropyl)-phthalimide 
• 50997-77-8 (2-bromo-1-methyl-ethyl)-phosphoramidic acid diethyl ester 

Downstream Products

• 56224-29-4 5-chloro-2,4-dinitro-N-(1-methyl-2-morpholin-4-yl-ethyl)-aniline 
• 56224-67-0 N,N'-bis-(1-methyl-2-morpholin-4-yl-ethyl)-4,6-dinitro-benzene-1,3-diamine 
• 93142-41-7 2,4-dimethyl-N-(1-methyl-2-morpholin-4-yl-ethyl)-benzamide 
• 1613696-57-3 4-(3,5-dimethyl-1,2-oxazol-4-yl)-N-[1-(morpholin-4-yl)propan-2-yl]-2-nitroaniline 

Relevant academic research and scientific papers

THIADIAZOLE-SUBSTITUTED ARYLAMIDES AS P2X3 AND P2X2/3 ANTAGONISTS

Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted thiadiazolyl, and R2, R3, R4, R5, R6, R7 and R8 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.

PYRIMIDINES WITH TIE2 (TEK) ACTIVITY

The invention relates to a compound of the Formula (I). or salt thereof wherein R1, R2, R3, R4, R5, R6, A, B, L, n and m are as defined in the description. The invention also relates to pharmaceutical compositions of said compounds, the use of said compounds as medicaments and in the production of an anti-angiogenic effect in a warm-blooded animal. The invention also relates to processes for the preparation of said compounds.

Nosylaziridines: Activated aziridine electrophiles

Nosylaziridines are highly reactive electrophiles towards a variety of nucleophiles yielding the corresponding SN2 adducts without competing attack on the nosyl functionality (SNAr). The resulting primary nosylamide adducts can he readily cleaved under mild conditions to provide the primary amines.

DIRECT NUCLEOPHILIC SUBSTITUTION IN 2-HALOALKYLAMINES: NEW ROUTE TO SUBSTITUTED ETHYLENEDIAMINES

Nucleophilic substitution in 2-haloalkylamines in weakly polar media was found to proceed partially without intermediate formation of aziridines.This makes it possible to obtain pure substituted ethylenediamines.