51003-31-7Relevant academic research and scientific papers
Assembly of Polysubstituted Maleimides via Palladium-Catalyzed Cyclization Reaction of Alkynes with Isocyanides
Hu, Weigao,Zheng, Jia,Li, Jianxiao,Liu, Bifu,Wu, Wanqing,Liu, Haiyang,Jiang, Huanfeng
, p. 12451 - 12458 (2016)
An efficient and convenient palladium-catalyzed cyclization reaction of alkynes with isocyanides is described herein. This protocol allows the practical synthesis of many valuable polysubstituted maleimide derivatives after hydrolysis with a broad scope of substrates and mild reaction conditions. C-C, CO, and C-N bonds were constructed in this transformation with isocyanide serving as both C and N sources.
