N-(GAMMA-L-GLUTAMYL)-1-NAPHTHYLAMIDE is a chemical compound extensively utilized in biochemical research, characterized by a naphthylamine moiety conjugated to a gamma-glutamyl group. It serves as a substrate for the enzyme gamma-glutamyltranspeptidase (GGT), which plays a crucial role in the metabolism of the antioxidant glutathione. This crystalline compound is soluble in water and alcohol, and its use in medical diagnostics is significant for detecting conditions such as liver disease, alcohol abuse, and infections where GGT levels may be elevated.
51012-91-1
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Basic information
- Product Name: N-(GAMMA-L-GLUTAMYL)-1-NAPHTHYLAMIDE
- Synonyms: N-(7-γ-glutamyl)-α-naphthylamide;N-(GAMMA-L-GLUTAMYL)-1-NAPHTHYLAMIDE;N-(γ-L-Glutamyl)-1-naphthylamide;N-(R-L-GUTAMYL)-1-NAPHTHYLAMIDE;N-(r-L-GlutaMyl)-1-naphthylaMide
- CAS NO:51012-91-1
- Molecular Formula: C16H16N2O4
- Molecular Weight: 300.30924
- EINECS: N/A
- Product Categories: N/A
- Mol File: 51012-91-1.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: N-(GAMMA-L-GLUTAMYL)-1-NAPHTHYLAMIDE(CAS DataBase Reference)
- NIST Chemistry Reference: N-(GAMMA-L-GLUTAMYL)-1-NAPHTHYLAMIDE(51012-91-1)
- EPA Substance Registry System: N-(GAMMA-L-GLUTAMYL)-1-NAPHTHYLAMIDE(51012-91-1)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 51012-91-1(Hazardous Substances Data)
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51012-91-1 Usage
Uses
Used in Medical Diagnostics:N-(GAMMA-L-GLUTAMYL)-1-NAPHTHYLAMIDE is used as a diagnostic agent for detecting elevated levels of the enzyme gamma-glutamyltranspeptidase (GGT) in patients, which can indicate conditions such as liver disease, alcohol abuse, and various infections.
Used in Biochemical Research:
In the field of biochemical research, N-(GAMMA-L-GLUTAMYL)-1-NAPHTHYLAMIDE is used as a substrate for studying the activity and function of the enzyme gamma-glutamyltranspeptidase (GGT), which is essential in the metabolism of the antioxidant glutathione.
Used in Pharmaceutical Development:
N-(GAMMA-L-GLUTAMYL)-1-NAPHTHYLAMIDE is employed as a potential therapeutic agent in the development of drugs targeting the enzyme GGT, which may have implications for treating conditions associated with its dysregulation.
Used in Toxicology Studies:
N-(GAMMA-L-GLUTAMYL)-1-NAPHTHYLAMIDE is utilized in toxicology studies to assess the impact of various substances on the activity of the enzyme GGT, providing insights into the mechanisms of toxicity and potential protective measures.
Used in Quality Control:
N-(GAMMA-L-GLUTAMYL)-1-NAPHTHYLAMIDE is used in the quality control of diagnostic assays and kits to ensure their accuracy and reliability in measuring GGT levels in biological samples.
When handling N-(GAMMA-L-GLUTAMYL)-1-NAPHTHYLAMIDE, it is important to follow basic safety precautions for bioactive compounds to minimize potential risks.
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N-(GAMMA-L-GLUTAMYL)-1-NAPHTHYLAMIDE
