51049-71-9

Upstream product

• 768-95-6 1-adamanthanol 
• 89-86-1 4-hydroxysalicylic acid 

Downstream Products

• 1313834-52-4 ((5-hydroxy-4-oxo-4H-pyran-2-yl)methyl 2,4-dihydroxy-5-adamantylbenzoate) 
• 1422043-80-8 5-adamantan-1-yl-N-(3,4-dihydroxybenzyl)-2,4-dihydroxy-benzoic acid amide 
• 1422043-92-2 5-adamantan-1-yl-N-(2,5-dimethoxybenzyl)-2,4-dihydroxy-benzoic acid amide 
• 1422043-78-4 5-adamantan-1-yl-N-[2-(3,4-dihydroxyphenyl)-ethyl]-2,4-dihydroxy-benzoic acid amide 
• 1422043-93-3 5-adamantan-1-yl-N-(2,5-dihydroxybenzyl)-2,4-dihydroxy-benzoic acid amide 
• 1422043-82-0 5-adamantan-1-yl-2,4-dihydroxy-N-[2-(4-hydroxyphenyl)-ethyl]-benzoic acid amide 
• 1422043-94-4 5-adamantan-1-yl-N-(3,5-dimethoxybenzyl)-2,4-dihydroxy-benzoic acid amide 
• 1365531-26-5 5-adamantan-1-yl-N-(2,4-dimethoxy-benzyl)-2,4-dihydroxy-benzamide 
• 1365531-19-6 5-adamantan-1-yl-N-(2,4-dihydroxybenzyl)-2,4-dihydroxy-benzoic acid amide 
• 1365531-28-7 5-adamantan-1-yl-2,4-dihydroxy-N-(4-hydroxy-benzyl)-benzamide 
• 1365531-27-6 5-adamantan-1-yl-2,4-dihydroxy-N-(2-hydroxy-benzyl)-benzamide 

Relevant academic research and scientific papers

Adamantyl N-benzylbenzamide: New series of depigmentation agents with tyrosinase inhibitory activity

A new series of polyhydroxylated N-benzylbenzamide derivatives containing an adamantyl moiety has been synthesized, and the depigmenting and tyrosinase inhibitory activities of the molecules were evaluated. The lipophilic character of the adamantyl moiety

3D-QSAR study of adamantyl N-benzylbenzamides as melanogenesis inhibitors

Three-dimensional quantitative structure-activity relationship (3D-QSAR) modeling, comparative molecular field analysis (CoMFA), and comparative molecular similarity indices analysis (CoMSIA) of polyhydroxylated N-benzylbenzamide derivatives containing an

NOVEL BENZOIC ACID AMIDE COMPOUND

The present invention relates to a novel benzoic acid amide derivative compound, isomers thereof, pharmaceutically acceptable salts thereof, prodrugs thereof, hydrates thereof, or solvates thereof. The novel compound has excellent skin whitening effects.

NOVEL BENZOIC ACID AMIDE COMPOUND

The present invention relates to a novel benzoic acid amide derivative compound, isomers thereof, pharmaceutically acceptable salts thereof, prodrugs thereof, hydrates thereof, or solvates thereof. The novel compound has excellent skin whitening effects.

Depigmenting activities of kojic acid derivatives without tyrosinase inhibitory activities

We synthesized benzoate ester derivatives of kojic acid with and without adamantane moiety. Benzoate derivatives 2a-e that did not contain an adamantane moiety showed potent tyrosinase inhibitory activities. However, depigmenting activity was not noted in a cell-based assay. Contrasting results were obtained for benzoate derivatives (3a-e) containing an adamantane moiety. Compounds 3a-e showed potent depigmenting activities without tyrosinase inhibitory activities. To the best of our knowledge, this is the first study showing the depigmenting activities of kojic acid derivatives without tyrosinase inhibitory activities.