51054-99-0

Basic information

• Product Name: (3-Bromo-pyridin-4-yl)-acetic acid ethyl ester
• Synonyms: (3-Bromo-pyridin-4-yl)-acetic acid ethyl ester;4-Pyridineacetic acid, 3-broMo-, ethyl ester;Ethyl 3-bromo-4-pyridineacetate;3-Bromo-4-pyridineacetic acid ethyl ester;Ethyl 2-(3-bromopyridin-4-yl)
• CAS NO: 51054-99-0
• Molecular Formula: C₉H₁₀BrNO₂
• Molecular Weight: 244.0852
• Mol File: 51054-99-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 296.305 °C at 760 mmHg
• Flash Point: 133.001 °C
• Appearance: /
• Density: 1.452 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 2.93±0.18(Predicted)
• CAS DataBase Reference: (3-Bromo-pyridin-4-yl)-acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3-Bromo-pyridin-4-yl)-acetic acid ethyl ester(51054-99-0)
• EPA Substance Registry System: (3-Bromo-pyridin-4-yl)-acetic acid ethyl ester(51054-99-0)

Safety Data

• Hazardous Substances Data: 51054-99-0(Hazardous Substances Data)

Usage

General Description

(3-Bromo-pyridin-4-yl)-acetic acid ethyl ester is a chemical compound with the molecular formula C10H10BrNO2. It is derived from pyridine and contains a bromine atom and an ethyl ester group. (3-Bromo-pyridin-4-yl)-acetic acid ethyl ester is commonly used in organic synthesis and pharmaceutical research due to its potential as a building block for the synthesis of various biologically active compounds. It has been studied for its potential pharmacological properties and may have applications in drug development. Additionally, it may also be used in the synthesis of various organic compounds for research and industrial purposes.

Upstream product

• 64-17-5 ethanol 
• 1227592-44-0 C₇H₆BrNO₂ 
• 3430-22-6 3-Bromo-4-methylpyridin 
• 105-58-8 Diethyl carbonate 

Downstream Products

• 1069115-10-1 ethyl 2-(3-bromopyridin-4-yl)-2-methylpropanoate 
• 1637752-28-3 spiro[cyclopropane-1,3'-pyrrolo[2,3-c]pyridin]-2'(1'H)-one 
• 1357481-27-6 2-(3-bromo-4-pyridyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide 

Relevant articles and documents

Borylation of Unactivated C(sp3)-H Bonds with Bromide as a Traceless Directing Group

A palladium-catalyzed alkyl C-H borylation with bromide as a traceless directing group is described, providing a convenient approach to access alkyl boronates bearing a β-all-carbon quaternary stereocenter. The protocol features a broad substrate scope, excellent site selectivity, and good functional group tolerance.

INDOLE AHR INHIBITORS AND USES THEREOF

The present invention provides compounds useful as inhibitors of AHR, compositions thereof, and methods of using the same.

One-pot synthesis of new aza- and diaza-aminophenanthrenes

The synthesis of a series of benzo(iso)quinoline and phenanthroline derivatives has been achieved using an efficient one-pot procedure. It proceeds through a Suzuki-Miyaura cross-coupling followed by a Dieckmann-Thorpe ring closure under microwave irradia