5106-58-1 Usage
General Description
2-Methyl-2-pyrazin-2-yl-propionitrile, also known as MPN, is a chemical compound with the molecular formula C8H8N2. It is commonly used as a reagent in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. MPN is a yellow liquid with a pungent odor and a boiling point of 211-213°C. It is also used as an intermediate in the synthesis of various organic compounds, including dyes, pigments, and flavors. MPN is known for its high reactivity and strong odor, and proper safety measures should be taken when handling this chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 5106-58-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,0 and 6 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5106-58:
(6*5)+(5*1)+(4*0)+(3*6)+(2*5)+(1*8)=71
71 % 10 = 1
So 5106-58-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H9N3/c1-8(2,6-9)7-5-10-3-4-11-7/h3-5H,1-2H3
5106-58-1Relevant articles and documents
Mild and practical method for the α-arylation of nitriles with heteroaryl halides
Klapars, Artis,Waldman, Jacob H.,Campos, Kevin R.,Jensen, Mark S.,McLaughlin, Mark,Chung, John Y. L.,Cvetovich, Raymond J.,Chen, Cheng-Yi
, p. 10186 - 10189 (2007/10/03)
A mild and transition-metal-free method for theα-arylation of a liphatic nitriles with activated heteroaryl halides was developed using NaHMDS o r KHMDS as base at ambient temperature. The key to the success of this method is generation of the nitrile anion in the presence of the heteroaryl halide. The method is applicable to both primary and secondary carbonitriles and a wide range of heteroaryl halides. Selective monoarylation was observed with primary carbonitriles. The operational simplicity and the mild reaction conditions add to the value of this methodas a practical alternative to the preparation of α-heteroaryl carbonitriles.
