51067-85-7

Basic information

• Product Name: METHYL 2-HYDROXYDODECANOATE
• Synonyms: METHYL 2-HYDROXYDODECANOATE;DL-ALPHA-HYDROXYLAURIC ACID METHYL ESTER;2-HYDROXY C12:0 METHYL ESTER;2-HYDROXY C14:0 METHYL ESTER;dl-A-hydroxylauric acid methyl ester;dl-α-hydroxylauric acid methyl ester;2-Hydroxydodecanoic acid methyl ester;2-Hydroxylauric acid methyl ester
• CAS NO: 51067-85-7
• Molecular Formula: C₁₃H₂₆O₃
• Molecular Weight: 230.34
• Mol File: 51067-85-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 277.2°C at 760 mmHg
• Flash Point: 118.5°C
• Appearance: /
• Density: 0.942g/cm³
• Vapor Pressure: 0.000568mmHg at 25°C
• Refractive Index: 1.448
• Storage Temp.: 2-8°C
• CAS DataBase Reference: METHYL 2-HYDROXYDODECANOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-HYDROXYDODECANOATE(51067-85-7)
• EPA Substance Registry System: METHYL 2-HYDROXYDODECANOATE(51067-85-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 51067-85-7(Hazardous Substances Data)

Usage

General Description

Methyl 2-hydroxydodecanoate is a chemical compound with the molecular formula C13H26O3. It is an ester, specifically a methyl ester of 2-hydroxydodecanoic acid. METHYL 2-HYDROXYDODECANOATE is commonly used in the production of cosmetics, personal care products, and pharmaceuticals as an emollient and skin conditioning agent. It has moisturizing and soothing properties, making it suitable for use in products such as lotions, creams, and ointments. Additionally, it can also be used as a fragrance ingredient in perfumes and other scented products. Methyl 2-hydroxydodecanoate is a versatile and widely used chemical in the beauty and pharmaceutical industries due to its beneficial properties for skincare and formulation flexibility.

InChI:InChI=1/C13H26O3/c1-3-4-5-6-7-8-9-10-11-12(14)13(15)16-2/h12,14H,3-11H2,1-2H3

Upstream product

• 18797-16-5 2-methoxy-dodecanoic acid methyl ester 
• 112-44-7 undecylaldehyde 
• 124838-36-4 1,1,1-tris(methylthio)-2-dodecanol 

Downstream Products

• 120977-26-6 C₂₀H₂₅F₅O₄ 

Relevant articles and documents

Gas chromatography/electron-capture negative ion mass spectrometry for the quantitative determination of 2- and 3-hydroxy fatty acids in bovine milk fat

2- and 3-hydroxy fatty acids (2- and 3-OH-FAs) are bioactive substances reported in sphingolipids and bacteria. Little is known of their occurrence in food. For this reason, a method suitable for the determination of OH-FAs at trace levels in bovine milk fat was developed. OH-FAs (and conventional fatty acids in samples) were converted into methyl esters and the hydroxyl group was derivatized with pentafluorobenzoyl (PFBO) chloride to give PFBO-O-FA methyl esters. These derivatives with strong electron affinity were determined by gas chromatography interfaced to mass spectrometry using electron-capture negative ion in the selected ion monitoring mode (GC/ECNI-MS-SIM). This method proved to be highly sensitive and selective for PFBO-O-FA methyl esters. For the analysis of samples, two internal standards were used. For this purpose, 9,10-dideutero-2-OH-18:0 methyl ester (ISTD-1) from 2-OH-18:1(9c) methyl ester as well as the ethyl ester of 3-PFBO-O-12:0 (ISTD-2) was synthesized. ISTD-1 served as a recovery standard whereas ISTD-2 was used for GC/MS measurements. The whole-sample cleanup consisted of accelerated solvent extraction of dry bovine milk, addition of ISTD 1, saponification, conversion of fatty acids into methyl esters by use of boron trifluoride, separation of the methyl esters of OH-FAs from nonsubstituted FAs on activated silica, conversion of OH-FAs methyl esters into PFBO-O-FA methyl esters, addition of ISTD-2, and measurement by GC/ECNI-MS-SIM. By this method, ten OH-FAs were quantified in bovine milk fat with high precision in the range from 0.02 ± 0.00 to 4.49 ± 0.29 mg/100 g of milk fat.