510713-42-5

Basic information

• Product Name: 5-[4-(dimethylamino)phenyl]-3-hydroxy-1-(2-hydroxypropyl)-4-(4-methylbenzoyl)-1,5-dihydro-2H-pyrrol-2-one
• Synonyms: 5-[4-(dimethylamino)phenyl]-3-hydroxy-1-(2-hydroxypropyl)-4-(4-methylbenzoyl)-1,5-dihydro-2H-pyrrol-2-one
• CAS NO: 510713-42-5
• Molecular Formula: C₂₃H₂₆N₂O₄
• Molecular Weight: 394.46354
• Mol File: 510713-42-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-[4-(dimethylamino)phenyl]-3-hydroxy-1-(2-hydroxypropyl)-4-(4-methylbenzoyl)-1,5-dihydro-2H-pyrrol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[4-(dimethylamino)phenyl]-3-hydroxy-1-(2-hydroxypropyl)-4-(4-methylbenzoyl)-1,5-dihydro-2H-pyrrol-2-one(510713-42-5)
• EPA Substance Registry System: 5-[4-(dimethylamino)phenyl]-3-hydroxy-1-(2-hydroxypropyl)-4-(4-methylbenzoyl)-1,5-dihydro-2H-pyrrol-2-one(510713-42-5)

Safety Data

• Hazardous Substances Data: 510713-42-5(Hazardous Substances Data)

Upstream product

• 100-10-7 4-dimethylamino-benzaldehyde 
• 122-00-9 para-methylacetophenone 
• 39848-01-6 2-hydroxy-4-oxo-4-p-tolyl-but-2-enoic acid methyl ester 
• 73825-92-0 1-(4-dimethylamino-benzylidenamino)-propan-2-ol 

Relevant articles and documents

Design, synthesis, and structure-activity relationship exploration of 1-substituted 4-aroyl-3-hydroxy-5-phenyl-1 H -pyrrol-2(5 H)-one analogues as inhibitors of the annexin A2′S100A10 protein interaction

S100 proteins are small adaptors that regulate the activity of partner proteins by virtue of direct protein interactions. Here, we describe the first small molecule blockers of the interaction between S100A10 and annexin A2. Molecular docking yielded cand