51072-16-3Relevant academic research and scientific papers
OXAZOLIDINES. 1. BASIC CATALYTIC DISPROPORTIONATION OF CYCLOHEXANOSPIRO-2-OXAZOLIDINES: SYNTHESIS OF N-SUBSTITUTED 4,5,6,7-TETRAHYDROINDOLES
Kukharev, B.F.,Stankevich, V.K.,Kukhareva, V.A.
, p. 437 - 439 (2007/10/02)
It has been shown that the basic catalytic disproportionation of cyclohexanospiro-2-oxazolidines in the presence of potasium hydroxide or sodium methylate leads to N-substituted 4,5,6,7-tetrahydroindoles with a yield of up to 73percent.The influence of the character of substituents at the nitrogen atom of oxazolidine on the course of the reaction has been established.
A Facile Route to 2-Substituted Indoles
Madsen, J.Oe.,Meldal. M.,Mortensen. S.,Olsson, B.
, p. 77 - 82 (2007/10/02)
Imines, derived from cyclohexanone and alkylamines, react with α-chloroacrylonitrile in the presence of triethylamine to give products which upon pyrolysis afford 1-alkyl-4,5,6,7-tetrahydroindoles.Substitution at the 2-position of these compounds followed
