510758-28-8

Basic information

• Product Name: TBTA
• Synonyms: Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)Methyl]aMine 97%;1-(1-Benzyltriazol-4-yl)-N,N-bis[(1-benzyltriazol-4-yl)methyl]methanamine;N,N,N-Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine;Tris-(benzyltriazolylmethyl)amine;Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine;Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine, 97% TBTA
• CAS NO: 510758-28-8
• Molecular Formula: C30H30N10
• Molecular Weight: 530.6262
• EINECS: -0
• Mol File: 510758-28-8.mol
• Article Data: 0

Chemical Properties

• Melting Point: 132-143℃
• Boiling Point: 762.4±70.0 °C(Predicted)
• Appearance: White/Solid
• Density: 1.27±0.1 g/cm3(Predicted)
• Storage Temp.: ?20°C
• Solubility: Soluble in DMSO, DMF.
• PKA: 2.44±0.50(Predicted)
• Stability: store cold
• CAS DataBase Reference: TBTA(CAS DataBase Reference)
• NIST Chemistry Reference: TBTA(510758-28-8)
• EPA Substance Registry System: TBTA(510758-28-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 510758-28-8(Hazardous Substances Data)

Usage

Description

TBTA was introduced shortly after the copper-catalyzed azide-alkyne cycloaddition reaction was discovered to mitigate thermodynamic instability of Cu(I) in aerobic media. TBTA is a water-insoluble ligand and must be first dissolved in DMSO or DMF. J Am Chem Soc., 143 (18), 6787-6791. T. R. Chan, R. Hilgraf, K. B. Sharpless, V. V. Fokin, Org. Lett. 2004, 6, 2853.

Uses

Tris-(benzyltriazolylmethyl)amine is a useful reagent for copper (I) catalyzed azide-alkyne cycloadditions.?It can also be used for postsynthetic labelling of alkyne-modified DNA.

Downstream Products

• 1402266-93-6 C₃₀H₂₉N₅O₆