51076-95-0

Basic information

• Product Name: 2-Chloro-1,1,1-triethoxyethane
• Synonyms: ORTHOCHLOROACETIC ACID TRIETHYL ESTER;O-CHLOROACETIC ACID TRIETHYL ESTER;TRIETHYL ORTHOCHLOROACETATE;TRIETHYL 2-CHLOROORTHOACETATE;2-CHLORO-1,1,1-TRIETHOXYETHANE;2-CHLORO-1,1,1-TRIETHOXYETHANE 96%;2-Chloro-1,1,1-triethoxyethane, Triethyl 2-chloroorthoacetate;Chloroorthoacetic acid triethyl ester
• CAS NO: 51076-95-0
• Molecular Formula: C₈H₁₇ClO₃
• Molecular Weight: 196.67
• Product Categories: Orthoesters
• Mol File: 51076-95-0.mol
• Article Data: 8

Chemical Properties

• Melting Point: 60-68 °C
• Boiling Point: 75-80 °C15 mm Hg
• Flash Point: 27 °F
• Appearance: clear colourless liquid
• Density: 1.031 g/mL at 20 °C(lit.)
• Vapor Pressure: 0.278mmHg at 25°C
• Refractive Index: n20/D 1.422
• Storage Temp.: Freezer
• CAS DataBase Reference: 2-Chloro-1,1,1-triethoxyethane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-1,1,1-triethoxyethane(51076-95-0)
• EPA Substance Registry System: 2-Chloro-1,1,1-triethoxyethane(51076-95-0)

Safety Data

• Hazard Codes: F,Xn,Xi
• Statements: 11-22-36/37/38
• Safety Statements: 16-26-36-37/39
• RIDADR: UN 1993 3/PG 2
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 51076-95-0(Hazardous Substances Data)

Usage

Chemical Properties

clear colourless liquid

InChI:InChI=1/C8H17ClO3/c1-4-10-8(7-9,11-5-2)12-6-3/h4-7H2,1-3H3

Upstream product

• 78-39-7 Triethyl orthoacetate 
• 64-17-5 ethanol 
• 74974-54-2 2-chloro-1,1,1-trimethoxyethane 
• 36743-66-5 ethyl chloroacetimidate hydrochloride 
• 37622-36-9 ethyl chloroacetimidate hydrochloride 
• 338-65-8 1-chloro-2,2-difluoroethane 
• 141-52-6 sodium ethanolate 

Downstream Products

• 64-17-5 ethanol 
• 74-85-1 ethene 
• 105-39-5 chloroacetic acid ethyl ester 
• 83767-36-6 2,5-Dichloro-3,4-dimethylene-hexanedioic acid diethyl ester 
• 50710-33-3 5,7-dichloro-2-chloromethyl-benzooxazole 
• 63842-22-8 5-chloro-2-(chloromethyl)-1,3-benzoxazole 
• 81494-05-5 2-chloro-N-(4-methoxybenzyl)acetamide 
• 208584-81-0 5-(chloromethyl)-1-(4-methoxybenzyl)-1H-tetrazole 
• 870559-13-0 (4S,5S)-2-(chloromethyl)-4,5-dihydro-4,5-diphenyl-1H-imidazole 
• 657424-52-7 2-chloromethyl-5-(2-fluoro-5-methyl-phenyl)-[1,3,4]oxadiazole 
• 623907-69-7 4'-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]-N-cyclopropyl-6-methyl-1,1'-biphenyl-3-carboxamide 
• 623907-60-8 4'-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]-N-cyclopropyl-5-fluoro-6-methyl-1,1'-bipheny1-3-carboxamide 
• 632334-68-0 2-chloromethyl-1H-thieno[3,4-d]imidazole 
• 110704-49-9 5-bromo-2-chloromethylbenzothiazole 

Relevant articles and documents

Synthesis method of crude carboxylic ester (by machine translation)

The method is characterized in that the carboxylic ester and the ether are prepared by reacting a carboxylic ester with an ether at a certain temperature under the catalysis of a catalyst at a certain pressure for a certain time. (by machine translation)

An efficient synthesis of 2,6-disubstituted benzobisoxazoles: New building blocks for organic semiconductors

(Chemical Equation Presented) 2,6-Disubstituted benzobisoxazoles have been synthesized by a highly efficient reaction of diaminobenzene diols with various orthoesters. The scope of this new reaction for the synthesis of substituted benzobisoxazoles has been investigated using four different orthoesters. The utility of these compounds as building blocks for the synthesis of conjugated polymers is demonstrated.

Synthesis of optically active 2-chloromethyl-2-oxazolines by the ortho- ester condensation method using triethyl orthochloroacetate

A set of optically active 2-chloromethyl-2-oxazolines was synthesized by condensation of optically active 2-amino alcohols with triethyl orthochloroacetate which was prepared conveniently from triethyl orthoacetate by chlorination using tert-butyl hypochlorite.