5108-94-1 Usage
Description
(16S,17R)-3-methoxy-13,16-dimethyl-7,8,9,11,12,14,15,17-octahydro-6H-cyclopenta[a]phenanthrene-16,17-diol is a steroid derivative belonging to the cyclopenta[a]phenanthrene family. It features a methoxy group at the 3 position and hydroxyl groups at the 16 and 17 positions, along with methyl groups at the 13 and 16 positions. The unique arrangement of these functional groups suggests potential biological activity, making it a candidate for pharmaceutical research and development.
Uses
Used in Pharmaceutical Research and Development:
(16S,17R)-3-methoxy-13,16-dimethyl-7,8,9,11,12,14,15,17-octahydro-6H-cyclopenta[a]phenanthrene-16,17-diol is used as a research compound for exploring its potential biological activity and therapeutic applications. Its unique structure and functional groups may contribute to its efficacy in treating specific medical conditions or diseases, warranting further investigation in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 5108-94-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,0 and 8 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5108-94:
(6*5)+(5*1)+(4*0)+(3*8)+(2*9)+(1*4)=81
81 % 10 = 1
So 5108-94-1 is a valid CAS Registry Number.
InChI:InChI=1/C20H28O3/c1-19-9-8-15-14-7-5-13(23-3)10-12(14)4-6-16(15)17(19)11-20(2,22)18(19)21/h5,7,10,15-18,21-22H,4,6,8-9,11H2,1-3H3/t15?,16?,17?,18-,19?,20+/m1/s1
5108-94-1Relevant articles and documents
Stereoselectivity in the epoxidation and cis-hydroxylation of 16-methylene-estra-1,3,5(10)-trienes
Bull, James R.,Kaiser, Delene A.
, p. 628 - 633 (1994)
Epoxidation of 3-methoxy-16-methylene-estra-1,3,5(10)-trien-17-one in the presence of alkaline hydrogen peroxide gives rise to (16R)- and (16S)-spiro in similar proportions.Epoxidation of the corresponding 16-methylene 17β-alcohol and 16-methylene-17β-acetate with m-chloroperbenzoic acid does not display any significant directing effects associated with allylic functionality, whereas Sharpless epoxidation of the 16-methylene 17β-alcohol is highly stereoselective, leading exclusively to the (16R) isomer. cis-Hydroxylation of the 16-methylene 17-ketone with osmium tetroxide/4-methylmorpholine-4-oxide proceeds stereoselectively to give mainly 16α-hydroxy-16β-hydroxymethyl-3-methoxyestra-1,3,5(10)-trien-17-one.The isomeric addition products derived from these reactions are correlated by appropriate interconversions, and the assignments are corroborated by comparative reactivity of derived products. - Keywords: estra-1,3,5(10)-trienes; 16-methylene-estra-1,3,5(10)-trienes; epoxidation; Sharpless epoxidation; hydroxylation