5109-46-6

Upstream product

• 408306-86-5 3-cyano-2-hydroxy-2-methyl-3-phenyl-propionic acid 
• 858805-59-1 2-hydroxy-2-methyl-3-phenyl-succinamic acid 

Relevant academic research and scientific papers

Pd-Catalyzed α-Selective C-H Functionalization of Olefins: En Route to 4-Imino-β-Lactams

Pd-catalyzed α-olefinic C-H activation of simple α,β-unsaturated olefins has been developed. 4-imino-β-lactam derivatives were readily synthesized via activation of α-olefinic C-H bonds with excellent cis stereoselectivity. A wide range of heterocycles at the β-position are compatible with this reaction. The product of 4-imino-β-lactam derivatives can be readily converted to 2-aminoquinoline which exists extensively in pharmaceutical drugs and natural products.