51102-41-1

Usage

Uses

Used in Chemical Industry:
3-METHYL-3,8-DIAZABICYCLO[3,2,1]OCTANE is used as a catalyst for [facilitating organic synthesis reactions] because of its ability to accelerate the formation of carbon-carbon bonds and aid in the synthesis of pharmaceutical compounds.
Used as a Ligand in Metal-Catalyzed Reactions:
In the field of catalysis, 3-METHYL-3,8-DIAZABICYCLO[3,2,1]OCTANE is used as a ligand to enhance the efficiency and selectivity of metal-catalyzed reactions, contributing to the advancement of chemical processes.
Used as a Chiral Auxiliary in Asymmetric Synthesis:
3-METHYL-3,8-DIAZABICYCLO[3,2,1]OCTANE is utilized as a chiral auxiliary in asymmetric synthesis for [improving the enantioselectivity of chemical reactions], which is crucial for the production of enantiomerically pure compounds, especially in pharmaceuticals.
Used in the Preparation of Organic Compounds:
As a reagent, 3-METHYL-3,8-DIAZABICYCLO[3,2,1]OCTANE is used in the preparation of various organic compounds, playing a significant role in the synthesis of a wide array of chemical products.
Used in Drug Delivery Systems:
3-METHYL-3,8-DIAZABICYCLO[3,2,1]OCTANE is studied for its potential use as a drug delivery system for [forming stable complexes with various molecules], which could improve the delivery, bioavailability, and therapeutic outcomes of drugs.

Downstream Products

• 1195779-07-7 6-[1-cyclobutyl-4-[(3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl]-1H-pyrazol-5-yl]-13-cyclohexyl-3-methoxy-N-[(1-methylethyl)sulfonyl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide 
• 1033904-12-9 8-cyclohexyl-11-methoxy-1a-((3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl)-N-((2,2,2-trifluoroethyl)sulfonyl)-1,1a,2,12b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide 
• 1127237-81-3 N-(cyclobutylsulfonyl)-13-cyclohexyl-3-methoxy-6-[1-methyl-4-[(3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl]-1H-pyrazol-5-yl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide 

Relevant academic research and scientific papers

COMPOUNDS, COMPOSITIONS, AND METHODS FOR SUPPRESSING TOXIC ENDOPLASMIC RETICULUM STRESS

The present invention provides, inter alia, a compound having the structure (I). Also provided are compositions containing a pharmaceutically acceptable carrier and one or more compounds according to the present invention. Further provided are methods for treating or ameliorating the effects of a disorder in a subject, methods of suppressing the toxicity of endoplasmic reticulum (ER) stress in a subject, methods of treating or ameliorating the effects of a disease involving axon degeneration in a subject, and methods for treating or ameliorating the effects of a neurodegenerative disease.

Diazabicyclooctanes and diazabicycloheptanes

Twelve analogs of diethylcarbamazine as prepared by acylation of 3- and 8-methyl-3,8-diazabicyclo[3.2.1]octane, 2-methyl-2,5-diazabicyclo[2.2.2]octane, and 2-methyl-2,5-diazabicyclo [2.2.1]heptane with diethylcarbamyl chloride, ethyl chloroformate, ethyl isocyanate, and cyclohexanecarbonyl chloride. These compounds are formally derived from diethylcarbamazine in possessing two- or one-carbon bridges over the piperazine ring. The compounds have utility as antifilarial agents and as bronchodilators.