511309-78-7

Upstream product

• 184305-30-4 [(5S)-2,2-Bis(trifluoromethyl)-5-methyl-4-oxo-1,3-dioxolan-5-yl] acetic acid 
• 6236-09-5 (S)-citramalic acid 
• 4132-27-8 1-amino-2,3,4,6-tetra-O-benzyl-1-deoxy-β-D-glucopyranose 
• 511309-74-3 ((S)-4-Methyl-5-oxo-2,2-bis-trifluoromethyl-[1,3]dioxolan-4-yl)-acetyl fluoride 
• 184305-31-5 [(5S)-2,2-Bis(trifluoromethyl)-5-methyl-4-oxo-1,3-dioxolan-5-yl] acetyl chloride 

Relevant academic research and scientific papers

Hexafluoroacetone as protecting and activating reagent. Glycosylated malic, citramalic, and thiomalic acid derivatives, new glycosylated building blocks for drug design

Glycosylated α-hydroxy and α-mercapto acids have been synthesized starting from malic/citramalic/thiomalic acid and Ac 4-β-D-Glc-NH2/Bzl4-β-D-Glc-NH 2 using hexafluoroacetone as protecting and activating reagent

New building blocks for peptide and depsipeptide modification N-glycosylated L-malic and L-citramalic acid derivatives

Neoglycoconjugates have been synthesized from L-malic acid/L-citramalic acid and β-D-Ac4Glc-NH2/β-D-Bzl4Glc-NH 2 using hexafluoroacetone as protecting and activating agent.