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1-(β-D-ribopyranosyl)thymine, also known as Thymine riboside or Thymd, is a nucleoside consisting of the base thymine attached to a β-D-ribofuranose sugar moiety. It is a derivative of the nucleoside thymidine, which is a key component of DNA. 1-(β-D-ribopyranosyl)thymine plays a significant role in the study of nucleic acid chemistry and the development of antiviral drugs, as it can be used to investigate the interactions between nucleosides and enzymes, as well as to develop new therapeutic strategies against viral infections. The presence of the ribose sugar in 1-(β-D-ribopyranosyl)thymine distinguishes it from its deoxyribose counterpart, thymidine, and influences its chemical properties and biological activities.

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  • 5115-03-7 Structure
  • Basic information

    1. Product Name: 1-(β-D-ribopyranosyl)thymine
    2. Synonyms: 1-(β-D-ribopyranosyl)thymine
    3. CAS NO:5115-03-7
    4. Molecular Formula:
    5. Molecular Weight: 258.231
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 5115-03-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-(β-D-ribopyranosyl)thymine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-(β-D-ribopyranosyl)thymine(5115-03-7)
    11. EPA Substance Registry System: 1-(β-D-ribopyranosyl)thymine(5115-03-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 5115-03-7(Hazardous Substances Data)

5115-03-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5115-03-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,1 and 5 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5115-03:
(6*5)+(5*1)+(4*1)+(3*5)+(2*0)+(1*3)=57
57 % 10 = 7
So 5115-03-7 is a valid CAS Registry Number.

5115-03-7Relevant articles and documents

Direct One-Pot Synthesis of Nucleosides from Unprotected or 5-O-Monoprotected d -Ribose

Downey, A. Michael,Richter, Celin,Pohl, Radek,Mahrwald, Rainer,Hocek, Michal

, p. 4604 - 4607 (2015)

New, improved methods to access nucleosides are of general interest not only to organic chemists but to the greater scientific community as a whole due their key implications in life and disease. Current synthetic methods involve multistep procedures employing protected sugars in the glycosylation of nucleobases. Using modified Mitsunobu conditions, we report on the first direct glycosylation of purine and pyrimidine nucleobases with unprotected d-ribose to provide β-pyranosyl nucleosides and a one-pot strategy to yield β-furanosides from the heterocycle and 5-O-monoprotected d-ribose.

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