511545-12-3

Upstream product

• 511544-67-5 dimethyl (S_s,1S,2R)-(+)-1-chloro-2-(4-trifluoromethylphenyl)-2-(p-toluenesulfinamido)ethylphosphonate 
• 511544-96-0 dimethyl (S_s,2S,3R)-(-)-N-(p-toluenesulfinyl)-3-(p-trifluoromethylphenyl)aziridine-2-phosphonate 

Relevant academic research and scientific papers

Asymmetric synthesis of aziridine 2-phosphonates from enantiopure sulfinimines (N-sulfinyl imines). Synthesis of α-amino phosphonates

An aza-Darzens reaction, involving the addition of chloromethylphosphonate anions to enantiopure sulfinimines, has been developed for the asymmetric synthesis of aziridine 2-phosphonates. Best results involve cyclization of the syn and anti diastereomeric