511549-17-0

Upstream product

• 874-42-0 2,4-dichlorobenzaldeyhde 
• 107-13-1 acrylonitrile 

Downstream Products

• 951380-59-9 [2-cyano-3-(2,4-dichloro-phenyl)-3-hydroxy-propylamino]-acetic acid methyl ester 
• 924658-71-9 2-[(4-chloro-phenylamino)-(2,4-dichloro-phenyl)-methyl]-acrylonitrile 
• 924658-69-5 2-[(2,4-dichlorophenyl)-phenylamino-methyl]-acrylonitrile 
• 367487-91-0 acetic acid 2-cyano-1-(2,4-dichloro-phenyl)-allyl ester 
• 874-42-0 2,4-dichlorobenzaldeyhde 

Relevant academic research and scientific papers

Fluorous tagging of DABCO through halogen bonding: Recyclable catalyst for the Morita-Baylis-Hillman reaction

The halogen-bonded adduct between DABCO and two molecules of perfluorooctyl iodide (DABCO·(C8F17I)2) acts as a recyclable organocatalyst for the Morita-Baylis-Hillman reaction. This "supramolecular fluorous catalyst" is re

N-Acylazole mediated stereoselective and regioselective synthesis of N-substituted azole acrylonitriles

Regio- and stereoselective synthesis of N -substituted azole acrylonitriles has been achieved smoothly in N, N -dimethylformamide (DMF) in the presence of potassium carbonate (K 2 CO 3) as a base catalyst. N -Substituted azole acrylonitriles were obtained

Design, synthesis, and biological evaluation of 4-H pyran derivatives as antimicrobial and anticancer agents

A series of pyran derivatives (5–27) were synthesized in good yields by utilizing Baylis–Hillman chemistry and were further investigated for their in vitro anticancer, antibacterial, and antifungal activities. Most of the tested compounds exhibited promis

Morita-Baylis-Hillman reaction in eutectic solvent under aqueous medium

A series of deep eutectic solvents (DESs) based on choline chloride were prepared and used in the Morita-Baylis-Hillman (M-B-H) reaction. Research showed that the composite solvent (1ChCl/2Gly DES-H2O) is a very effective solvent media for all

Cl-H2O: An efficient and versatile solvent system for the DABCO-catalyzed Morita-Baylis-Hillman reaction

An efficient and versatile solvent-catalyst system, [HyEtPy]Cl-H2O-DABCO, has been developed and used in the Morita-Baylis-Hillman reaction. Under the mild reaction conditions, Morita-Baylis-Hillman proceeds very quickly and efficiently. This protocol has notable advantages such as eco-friendliness, ease of work-up and reuse of ionic liquid conveniently, which could help reduce disposal costs and contribute to the development of a new solvent-catalyst system for use in green and continuous chemical processes.

Electrophilic warhead-based design of compounds preventing NLRP3 inflammasome-dependent pyroptosis

Pyroptosis is a caspase-1-dependent pro-inflammatory form of programmed cell death implicated in the pathogenesis of autoinflammatory diseases as well as in disorders characterized by excessive cell death and inflammation. Activation of NLRP3 inflammasome

Novel Sc(OTf)3/3-HQD catalyst for Morita-Baylis-Hillman reaction

A novel and efficient catalytic system of the Morita-Baylis-Hillman (MBH) reaction between aromatic aldehyde and activated alkenes has been developed. The novel system of a combination of Sc(OTf)3 and 3-hydroxyquinuclidine (3-HQD) showed a high catalytic

N-methylpiperidine - A useful base catalyst in the Morita-Baylis-Hillman reaction

N-methylpiperidine, a commercially available mild base, has effectively been utilized as a catalyst in the Morita-Baylis-Hillman reaction. Moderate to excellent yields (34-95%) and significant rate enhancement have been observed. Copyright Taylor & Franci