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3-Deaza-4-deoxyuridine is a synthetic nucleoside analog that is structurally similar to uridine, a naturally occurring nucleoside in RNA. It is characterized by the replacement of the nitrogen atom at the third position of the pyrimidine ring with a carbon atom, and the absence of an oxygen atom at the fourth position. This modification results in a molecule that can be incorporated into RNA during transcription, potentially affecting the stability and function of the resulting RNA molecules. 3-Deaza-4-deoxyuridine has been studied for its potential applications in antiviral and anticancer therapies, as well as its ability to modulate gene expression and interfere with viral replication. Its unique structure allows it to interact with enzymes and cellular machinery in ways that can lead to the inhibition of certain biological processes, making it a subject of interest in medicinal chemistry and drug development.

5116-37-0

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5116-37-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5116-37-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,1 and 6 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5116-37:
(6*5)+(5*1)+(4*1)+(3*6)+(2*3)+(1*7)=70
70 % 10 = 0
So 5116-37-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H13NO5/c12-5-6-8(14)9(15)10(16-6)11-4-2-1-3-7(11)13/h1-4,6,8-10,12,14-15H,5H2/t6-,8-,9-,10-/m1/s1

5116-37-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[(1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]pyridin-2-one

1.2 Other means of identification

Product number -
Other names 3-Deaza-4-deoxyuridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5116-37-0 SDS

5116-37-0Relevant academic research and scientific papers

Synthesis of pyridinone ribonucleoside 3'-O-phosphoramidites and their incorporation into oligoribonucleotides

Matulic-Adamic,Gonzalez,Usman,Beigelman

, p. 373 - 378 (2007/10/03)

Protected pyridin-2- and pyridin-4-one ribonucleosides 3 and 9 were synthesized using a one-pot reaction of silylated bases with 1-O-acetyl-tri-O-benzoyl-β-D-ribofuranose (2) in the presence of CF3SO3SiMe3. The nucleosides were converted in 4 steps into 3'-O-phosphoramidites 7 and 11 which were incorporated into hammerhead ribozyme substrates using solid-phase phosphoramidite chemistry.

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